Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | ANPEP | P15144 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367126 | 0.80 | MMP2 (0.46) | MMP2ANPEPCA12CA1CA2 | |
| SCHEMBL27640305 | 0.78 | ALDH1A1 (0.47) | MMP2ANPEPALDH1A1KMT2A | |
| SCHEMBL8342433 | 0.78 | ALDH1A1 (0.47) | MMP2ANPEPALDH1A1KMT2A | |
| SCHEMBL8107792 | 0.78 | ALDH1A1 (0.47) | MMP2ANPEPALDH1A1KMT2A | |
| SCHEMBL3476452 | 0.78 | MMP2 (0.53) | MMP2ANPEPCA12CA1CA2 | |
| SCHEMBL14367083 | 0.75 | MMP2 (0.43) | MMP2ANPEPCA12CA1CA2 | |
| SCHEMBL8098466 | 0.73 | MMP2 (0.33) | MMP2ANPEP | |
| SCHEMBL21702575 | 0.73 | MMP2 (0.49) | MMP2ANPEPCA12CA1CA2 | |
| SCHEMBL5691732 | 0.72 | MMP2 (0.48) | MMP2ANPEPALDH1A1 | |
| SCHEMBL14938109 | 0.72 | MMP2 (0.51) | MMP2ANPEPCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |