Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099435 | 0.91 | GABRA5 (0.36) | GABRA5PPARGSCN9ASCN5A | |
| SCHEMBL8916805 | 0.87 | GABRA5 (0.39) | GABRA5PPARGXDHALOX5SMPD1 | |
| SCHEMBL8767779 | 0.87 | GABRA5 (0.39) | GABRA5PPARGSCN9ASCN5ASMPD1 | |
| SCHEMBL8766955 | 0.84 | MGLL (0.39) | PPARGSCN9ASMPD1PTPN1 | |
| SCHEMBL8767147 | 0.84 | MGLL (0.39) | PPARGSCN9ASMPD1PTPN1 | |
| SCHEMBL8874638 | 0.78 | GABRA5 (0.38) | GABRA5PPARGSMPD1 | |
| SCHEMBL8090622 | 0.78 | SMN1; SMN2 (0.39) | GABRA5PPARGSCN9ASCN5A | |
| SCHEMBL8098997 | 0.75 | PPARG (0.45) | PPARGSMPD1 | |
| SCHEMBL8915506 | 0.75 | EGLN1 (0.43) | GABRA5SMPD1 | |
| SCHEMBL8099518 | 0.74 | PPARG (0.40) | PPARGSCN9ASCN5ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673931-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |