Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.69 |
| ▸ | HTR3B | O95264 | 2/20 | 0.69 |
| ▸ | HTR3A | P46098 | 2/20 | 0.69 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.69 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | HTR1D | P28221 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | HTR6 | P50406 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | HTR7 | P34969 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094745 | 0.83 | ALDH1A1 (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL231692 | 0.83 | ALDH1A1 (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Phenylpiperazine SCHEMBL3440604 | 0.82 | HTR3A (0.84) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL720648 | 0.82 | THRB (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Bromide SCHEMBL9146763 | 0.82 | ALDH1A1 (0.97) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL12818335 | 0.82 | THRB (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Piperazine SCHEMBL28225297 | 0.80 | THRB (0.97) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL379 | 0.80 | HTR3A (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29396943 | 0.80 | HTR3A (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6366499 | 0.80 | HTR3A (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |