SCHEMBL810384

SCHEMBL810384

[CH2]c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
TSHR P16473 5/20 0.43
HSD17B10 Q99714 5/20 0.43
CYP2A6 P11509 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
DHFR P00374 1/20 0.42
KDM4E B2RXH2 2/20 0.41
PTPN1 P18031 1/20 0.41
ALPL P05186 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 1/20 0.41
KEAP1 Q14145 1/20 0.41
NISCH Q9Y2I1 1/20 0.40
HPRT1 P00492 1/20 0.40
POLB P06746 1/20 0.39
MAPK1 P28482 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
ATM Q13315 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2491515 0.85 DHFR (0.46) ALDH1A1TSHRHSD17B10CYP2A6TDP1
SCHEMBL25302086 0.84 ALDH1A1 (0.59) ALDH1A1TSHRHSD17B10CYP2A6TDP1
SCHEMBL27953 0.84 ALDH1A1 (0.59) ALDH1A1TSHRHSD17B10CYP2A6TDP1
SCHEMBL29350007 0.84 ALDH1A1 (0.59) ALDH1A1TSHRHSD17B10CYP2A6TDP1
SCHEMBL2638067 0.82 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10CYP2A6TDP1
Bromide SCHEMBL8588309 0.82 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10CYP2A6TDP1
SCHEMBL6077039 0.82 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10CYP2A6TDP1
SCHEMBL17836548 0.82 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10CYP2A6TDP1
SCHEMBL18174178 0.82 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10CYP2A6TDP1
Hydrochloric Acid SCHEMBL4268575 0.82 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10CYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110684043-B C-N axis chiral arylamine compound and preparation method thereof 温州大学 2022-09-06 CN claimed
CN-112225685-B 3-cyanoindole compound, preparation method and application thereof 温州大学 2022-04-08 CN claimed
CN-111825508-B Preparation method of dihydro 9-phenanthrene amine compound and chiral product prepared by same 中国科学院化学研究所 2021-11-16 CN claimed
CN-112225685-A 3-cyanoindole compound, preparation method and application thereof 温州大学 2021-01-15 CN claimed
CN-111848322-A Axial chiral oxindole-substituted styrene compound and resolution method and application thereof 江苏师范大学 2020-10-30 CN claimed
CN-111825508-A Preparation method of dihydro 9-phenanthrene amine compound and chiral product prepared by same 中国科学院化学研究所 2020-10-27 CN claimed
CN-104892471-B Substance having protein tyrosine kinase inhibitory activity, preparation method and use thereof 中国人民解放军军事医学科学院放射与辐射医学研究所 2020-03-27 CN claimed
CN-107286089-B O-bicyclic amine compound, preparation method thereof and chiral product 中国科学院化学研究所 2020-03-10 CN claimed
CN-110684043-A C-N axis chiral arylamine compound and preparation method thereof 温州大学 2020-01-14 CN claimed
US-20190284134-A1 SULFONIUM SALT, HEAT- OR PHOTO-ACID GENERATOR, HEAT- OR PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT THEREOF SAN APRO LTD. (JP) 2019-09-19 US claimed
EP-3492476-A1 SULFONIUM SALT, HEAT- OR PHOTO-ACID GENERATOR, HEAT-CURABLE OR PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF San-Apro Ltd. (JP) 2019-06-05 EP claimed
CN-205435682-U A reation kettle throws material device for producing 2 - naphthyl benzyl ether 潍坊大有生物化工有限公司 2016-08-10 CN claimed
CN-205435702-U A conduction oil cooling device for producing 2 - naphthyl benzyl ether 潍坊大有生物化工有限公司 2016-08-10 CN claimed
CN-104130176-A 1, 5-disubstituted indolone derivative and application thereof UNIV TIANJIN SCIENCE & TECH 2014-11-05 CN claimed
CN-104130175-A Different-position substituted indolone derivatives and application thereof UNIV TIANJIN SCIENCE & TECH 2014-11-05 CN claimed
US-5726306-A INHIBITORS OF SQUALENE SYNTHETASE AND FUNGAL GROWTH; USEFUL IN TREATING AND PREVENTING HYPERLIPIDEMIA TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US claimed
CN-118184648-A Pyrrolo [3,4-c ] quinoline compound, synthesis method and application thereof 三峡大学 2024-06-14 CN disclosed
CN-110099966-B Colorant composition, colorant dispersion liquid, photosensitive resin composition, color filter and liquid crystal display device 株式会社LG化学 2024-05-07 CN disclosed
EP-0073569-A1 Process for the continuous production of alcohols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-09 EP disclosed
US-4061746-A Lactamimide inhibitors of gastrointestinal hypersecretion RICHARDSON-MERRELL INC. (US) 1977-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190284134-A1 SULFONIUM SALT, HEAT- OR PHOTO-ACID GENERATOR, HEAT- OR PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT THEREOF TST, MPST, ASIC1 ALDH1A1 1326/4885TSHR 1442/4885HSD17B10 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.