Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103949 | 0.84 | LMNA (0.59) | SMN1; SMN2ALDH1A1HTTLMNAMGLL | |
| SCHEMBL8096543 | 0.78 | FAAH (0.49) | SMN1; SMN2RECQLMAPTGAA | |
| SCHEMBL8104005 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2RECQLALDH1A1HTTLMNA | |
| SCHEMBL7314720 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2RECQLALDH1A1HTTLMNA | |
| SCHEMBL7314715 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2RECQLALDH1A1HTTLMNA | |
| SCHEMBL8096418 | 0.72 | FPR2 (0.46) | SMN1; SMN2LMNAMAPTEPHX2 | |
| SCHEMBL19317518 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HTTMGLLMAPK1KDM2B | |
| SCHEMBL31279890 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HTTMGLLMAPK1KDM2B | |
| SCHEMBL11614797 | 0.71 | ALDH1A1 (0.73) | SMN1; SMN2RECQLALDH1A1HTTLMNA | |
| SCHEMBL8105690 | 0.71 | LMNA (0.59) | SMN1; SMN2ALDH1A1HTTLMNAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |