Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MYOC | Q99972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246751 | 0.85 | KMT2A (0.45) | KMT2AL3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL8094492 | 0.85 | MAPK8 (0.41) | ALDH1A1HTTMAPK8GAA | |
| SCHEMBL7088107 | 0.79 | ROCK2 (0.58) | KMT2AL3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL7232438 | 0.78 | GLS (0.43) | L3MBTL1ALDH1A1MAPTMAPK8POLB | |
| SCHEMBL7231664 | 0.78 | KMT2A (0.41) | KMT2AL3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL7998311 | 0.77 | GLS (0.44) | L3MBTL1ALDH1A1MAPTMAPK8POLB | |
| SCHEMBL7994626 | 0.77 | GLS (0.42) | L3MBTL1ALDH1A1MAPTMAPK8POLB | |
| SCHEMBL8094494 | 0.76 | MAPK8 (0.44) | ALDH1A1MAPTMAPK8LMNARAB9A | |
| SCHEMBL8663662 | 0.73 | ALDH1A1 (0.47) | KMT2AL3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL4290852 | 0.71 | ALDH1A1 (0.44) | KMT2AL3MBTL1ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991631-A1 | SUBSTITUTED AMINOHETEROCYCLYLAMIDES | Bayer Aktiengesellschaft (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000375-A1 | SUBSTITUTED AMINOHETEROCYCLYLAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | WO | disclosed |