Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.40 |
| ▸ | PRKACA | P17612 | 4/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094492 | 0.90 | MAPK8 (0.41) | MAPK8ALDH1A1GLS | |
| SCHEMBL7998311 | 0.83 | GLS (0.44) | MAPK8ALDH1A1RAB9AMAPTGLS | |
| SCHEMBL7994626 | 0.80 | GLS (0.42) | MAPK8ALDH1A1RAB9AMAPTGLS | |
| SCHEMBL8069562 | 0.76 | MAPK8 (0.47) | MAPK8RAB9ALMNAMAPTRORC | |
| SCHEMBL8104093 | 0.76 | KMT2A (0.49) | MAPK8ALDH1A1RAB9ALMNAMAPT | |
| SCHEMBL7230936 | 0.76 | GAA (0.47) | MAPK8ALDH1A1CSNK1D | |
| SCHEMBL8094581 | 0.75 | SMN1; SMN2 (0.40) | MAPK8ALDH1A1RAB9ALMNAMAPT | |
| SCHEMBL7232438 | 0.72 | GLS (0.43) | MAPK8ALDH1A1RAB9AROCK1LMNA | |
| SCHEMBL7997967 | 0.72 | KDM4E (0.41) | ALDH1A1RAB9ACSNK1DLMNAMAPT | |
| SCHEMBL7996112 | 0.70 | RAB9A (0.51) | MAPK8ALDH1A1RAB9ACSNK1DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991631-A1 | SUBSTITUTED AMINOHETEROCYCLYLAMIDES | Bayer Aktiengesellschaft (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000375-A1 | SUBSTITUTED AMINOHETEROCYCLYLAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | WO | disclosed |