Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL8120160 | 0.97 | CLCN2 (0.37) | CLCN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL8114342 | 0.82 | CLCN2 (0.42) | CLCN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10276952 | 0.81 | CLCN2 (0.43) | CLCN2TSHRALDH1A1MEN1KMT2A | |
| Potassium Ion SCHEMBL8104738 | 0.77 | ALDH1A1 (0.48) | CLCN2TSHRALDH1A1F2RGABRA1 | |
| SCHEMBL8114356 | 0.75 | ERCC5 (0.43) | POLBHTT | |
| SCHEMBL3364147 | 0.74 | CLCN2 (0.41) | CLCN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29532527 | 0.74 | CLCN2 (0.41) | CLCN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL6912609 | 0.74 | ALDH1A1 (0.48) | CLCN2TSHRALDH1A1F2RGABRA1 | |
| SCHEMBL6912938 | 0.74 | ALDH1A1 (0.48) | CLCN2TSHRALDH1A1F2RGABRA1 | |
| SCHEMBL8877744 | 0.74 | ALDH1A1 (0.54) | CLCN2TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6126855-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 2000-10-03 | — | — | US | disclosed |
| US-5833877-A | DIAGMAGNETIC COMPLEX; SUPERCONDUCTORS | ELLIOTT STANLEY B (US) | 1998-11-10 | — | — | US | disclosed |
| US-5595683-A | COMPLEX OF METAL SALT OF BENZOYLPROPIONIC ACID, LATTICE MODIFIER, CYCLIZATION, HUMIDITY SENSORS | ELLIOTT STANLEY B (US) | 1997-01-21 | — | — | US | disclosed |
| US-5443753-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 1995-08-22 | — | — | US | disclosed |
| US-5354499-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 1994-10-11 | — | — | US | disclosed |
| US-5354496-A | Lyotropic liquid crystal salt/inorganic compound complexation products | ELLIOTT STANLEY B (US) | 1994-10-11 | — | — | US | disclosed |