Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104244 | 0.94 | THRB (0.40) | ADRB1ADRB3POLBALDH1A1MAPT | |
| SCHEMBL8118821 | 0.88 | ALDH1A1 (0.40) | POLBALDH1A1MAPTPSMB5MCHR1 | |
| SCHEMBL8113210 | 0.86 | ALDH1A1 (0.41) | POLBALDH1A1MAPTPSMB5MCHR1 | |
| Hydrochloric Acid SCHEMBL8118836 | 0.85 | F10 (0.42) | NLRP3ADRB1ADRB3MAPTLMNA | |
| SCHEMBL8112927 | 0.84 | MCHR1 (0.37) | POLBALDH1A1MAPTPSMB5MCHR1 | |
| SCHEMBL8104036 | 0.80 | MCHR1 (0.38) | ALDH1A1MAPTPSMB5MCHR1PANK3 | |
| SCHEMBL8122191 | 0.80 | POLB (0.56) | POLBALDH1A1MAPTPSMB5MCHR1 | |
| SCHEMBL8118092 | 0.80 | NLRP3 (0.46) | NLRP3POLBALDH1A1MAPTPSMB5 | |
| SCHEMBL28742149 | 0.79 | POLB (0.47) | NLRP3POLBALDH1A1MAPTPSMB5 | |
| Hydrochloric Acid SCHEMBL8105346 | 0.79 | F10 (0.42) | NLRP3ADRB1ADRB3POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |