Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107951 | 0.85 | RAB9A (0.49) | HSD17B10POLBKDM4EALDH1A1GAA | |
| SCHEMBL8116289 | 0.84 | ALOX15 (0.60) | MAPK1ALOX15HSD17B10SMN1; SMN2POLB | |
| SCHEMBL8121709 | 0.82 | HSD17B10 (0.54) | ALOX15HSD17B10SMN1; SMN2POLBKDM4E | |
| SCHEMBL8123100 | 0.77 | ALDH1A1 (0.44) | MAPK1HSD17B10SMN1; SMN2POLBKDM4E | |
| SCHEMBL8104888 | 0.77 | PTK2B (0.54) | HSD17B10SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL5525906 | 0.75 | CASP3 (0.64) | HSD17B10KDM4EALDH1A1HPGDCASP3 | |
| SCHEMBL12268174 | 0.75 | PTGS2 (0.60) | MAPK1HSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL2442267 | 0.74 | KDM4E (0.65) | MAPK1ALOX15HSD17B10SMN1; SMN2POLB | |
| SCHEMBL29483352 | 0.74 | KDM4E (0.65) | MAPK1ALOX15HSD17B10SMN1; SMN2POLB | |
| SCHEMBL9511333 | 0.73 | KMT2A (0.56) | SMN1; SMN2ALDH1A1TDP1L3MBTL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |