SCHEMBL811769

SCHEMBL811769

Oc1ccc(SCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.36
KCNH2 Q12809 1/20 0.36
CA2 P00918 2/20 0.35
NR1H2 P55055 1/20 0.33
LMNA P02545 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL811000 1.00 HSP90AA1 (0.36) HSP90AA1KCNH2CA2NR1H2LMNA
SCHEMBL21219435 0.89 ALDH1A1 (0.34) CA2
SCHEMBL8484616 0.83 ALDH1A1 (0.48) LMNA
SCHEMBL12817964 0.80
SCHEMBL4418190 0.76 THRA (0.44) HSP90AA1KCNH2CA2
SCHEMBL4414910 0.76 THRA (0.44) HSP90AA1KCNH2CA2
SCHEMBL8770515 0.74
SCHEMBL7156898 0.74 ESR1 (0.46) CA2LMNAESR1ESR2
SCHEMBL9146595 0.71 LTA4H (0.43) LMNAESR1ESR2
SCHEMBL10407904 0.71 NR1H2 (0.55) HSP90AA1KCNH2CA2NR1H2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785123-B2 Direct hierarchical assembly of nanoparticles THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-07-22 US claimed
US-20120309904-A1 Direct Hierarchical Assembly of Nanoparticles THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-12-06 US claimed
WO-2011047386-A1 DIRECT HIERARCHICAL ASSEMBLY OF NANOPARTICLES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-04-21 WO claimed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
US-8785123-B2 Direct hierarchical assembly of nanoparticles THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-07-22 US disclosed
US-20120309904-A1 Direct Hierarchical Assembly of Nanoparticles THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-12-06 US disclosed
EP-2389399-A2 FUNCTIONALIZED POLYURETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF Construction Research & Technology GmbH (DE) 2011-11-30 EP disclosed
US-20110256438-A1 WOUND-TYPE ACCUMULATOR JM ENERGY CORPORATION (JP) 2011-10-20 US disclosed
WO-2011047386-A1 DIRECT HIERARCHICAL ASSEMBLY OF NANOPARTICLES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-04-21 WO disclosed
US-20100324205-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2010-12-23 US disclosed
WO-2008040428-A2 FUNCTIONALIZED POLYURETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2008-04-10 WO disclosed
US-20060128957-A1 Fluorous tagging and scavenging reactants and methods of synthesis and use thereof FLUOROUS TECHNOLOGIES INCORPORATED 2006-06-15 US disclosed
US-7060850-B2 Fluorous tagging and scavenging reactants and methods of synthesis and use thereof FLUOROUS TECHNOLOGIES INCORPORATED (US) 2006-06-13 US disclosed
US-20040073054-A1 New fluorous tagging and scavenging reactants and methods of synthesis and use thereof FLUOROUS TECHNOLOGIES, INC. 2004-04-15 US disclosed
EP-0468531-B2 2-Diazo-1,2-quinone compounds and image forming materials prepared using the compounds FUJI PHOTO FILM CO LTD (JP) 1997-11-12 EP disclosed
US-5514518-A CHANGE IN POLARITY UPON EXPOSURE REDUCES ADHESIVENESS FUJI PHOTO FILM CO., LTD. (JP) 1996-05-07 US disclosed
US-5384227-A Optical recording material with supports and light sensitive layers, for receiver sheets, photoresists and printing plates FUJI PHOTO FILM CO., LTD. (JP) 1995-01-24 US disclosed
US-5312905-A Image forming materials FUJI PHOTO FILM CO., LTD. (JP) 1994-05-17 US disclosed
EP-0468531-A1 2-Diazo-1,2-quinone compounds and image forming materials prepared using the compounds FUJI PHOTO FILM CO., LTD. (JP) 1992-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040073054-A1 New fluorous tagging and scavenging reactants and methods of synthesis and use thereof THEM6, NOTUM, RNF31 HSP90AA1 4545/4885KCNH2 4554/4885CA2 3304/4885
US-20060128957-A1 Fluorous tagging and scavenging reactants and methods of synthesis and use thereof PFAS, CTSF, AFF2 HSP90AA1 4463/4885KCNH2 4514/4885CA2 3196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.