SCHEMBL812183

SCHEMBL812183

O=C(OCc1ccccc1)C(O)CO

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
TDP1 Q9NUW8 2/20 0.53
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
KMT2A Q03164 1/20 0.53
LMNA P02545 3/20 0.49
HCAR2 Q8TDS4 1/20 0.49
LTA4H P09960 1/20 0.47
LAP3 P28838 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CTRB1 P17538 2/20 0.44
CDC25B P30305 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25780163 1.00 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL874182 0.85 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL23843033 0.85 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL4219709 0.85 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL262278 0.85 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL7046944 0.85 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL5768186 0.83 ALDH1A1 (0.58) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL6945759 0.83 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL15717676 0.83 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL1133837 0.83 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344256-B1 SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF ELIZABETH ARDEN INT SARL (CH) 2017-04-26 EP claimed
CN-102231996-B Skin treatment agent comprising carboxylic acid-substituted idebenone derivative, and preparation method and use thereof ARDEN ELIZABETH INC 2014-11-26 CN claimed
CN-102231996-A Skin treatment agent comprising carboxylic acid-substituted idebenone derivative, and preparation method and use thereof PHARMA COSMETIX RES LLC 2011-11-02 CN claimed
EP-2344256-A2 SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF Elizabeth Arden International, Sarl (CH) 2011-07-20 EP claimed
WO-2010051138-A2 SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF PHARMA COSMETIX RESEARCH, LLC (US) 2010-05-06 WO claimed
US-20100086494-A1 SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF PCR TECHNOLOGY HOLDINGS, LC (US) 2010-04-08 US claimed
US-12595265-B2 Inhibitors of activin receptor-like kinase BLUEPRINT MEDICINES CORPORATION (US) 2026-04-07 US disclosed
WO-2025132660-A1 METHOD FOR TREATING HUMAN PERSPIRATION, AND ASSOCIATED COMPOSITION L'OREAL (FR) 2025-06-26 WO disclosed
US-20250009621-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING ALPHA HYDROXY ACID ESTER L'OREAL (FR) 2025-01-09 US disclosed
WO-2025006991-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING ALPHA HYDROXY ACID ESTER L'OREAL (FR) 2025-01-02 WO disclosed
US-20240158398-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORPORATION 2024-05-16 US disclosed
EP-4285996-A2 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE Blueprint Medicines Corporation (US) 2023-12-06 EP disclosed
EP-3442977-B1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORP (US) 2023-06-28 EP disclosed
EP-0098020-A2 Imaging film and film-forming composition, method for recording electromagnetic radiation, quinone compounds and method of synthesizing quinone compounds ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP disclosed
EP-0098019-A2 Imaging film and composition including a tellurium compound and method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP disclosed
EP-0098018-A2 Imaging film and composition employing an organo-metallic compound and method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP disclosed
US-4340662-A PHOTOSENSITIVE FILMS ENERGY CONVERSION DEVICES, INC. (US) 1982-07-20 US disclosed
US-4281058-A A PHOTOSENSITIVE COMPLEX OF THE TELLURIUM COMPOUND AND A GLYCEROL ETHER OR THIOETHER; NONSILVER PHOTOGRAPHY ENERGY CONVERSION DEVICES, INC. (US) 1981-07-28 US disclosed
US-4127730-A Method of preparing polymers analogous to enzymes DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-11-28 US disclosed
US-4111863-A NON-SWELLABLE, THREE DIMENSIONAL DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158398-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE ACVR1, ACVR2A, ACVRL1 ALDH1A1 3277/4885TDP1 2048/4885MAPK1 652/4885
US-20250009621-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING ALPHA HYDROXY ACID ESTER EBP, ADH1A, ADH1C ALDH1A1 119/4885TDP1 949/4885MAPK1 2793/4885
US-20100086494-A1 SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF CUTA, HSD17B12, NDUFB10 ALDH1A1 312/4885TDP1 3996/4885MAPK1 3754/4885
US-12595265-B2 Inhibitors of activin receptor-like kinase ACVR1, ACVRL1, ACVR2A ALDH1A1 2050/4885TDP1 2431/4885MAPK1 742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.