Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213108 | 0.81 | MEN1 (0.40) | TSHRKCNH2NPSR1 | |
| SCHEMBL812047 | 0.80 | ALDH1A1 (0.44) | TSHRCA1CA2CA5ACA9 | |
| SCHEMBL812265 | 0.78 | KIF11 (0.52) | MAPTNPC1RAB9AKIF11 | |
| SCHEMBL1338196 | 0.78 | CA12 (0.42) | CA1CA2CA9ACHETDP1 | |
| SCHEMBL295494 | 0.76 | LMNA (0.40) | ACHETDP1KCNH2MAPTRAB9A | |
| SCHEMBL8354614 | 0.76 | TSHR (0.48) | TSHRCA1CA2CA5ACA9 | |
| SCHEMBL19426802 | 0.70 | TSHR (0.46) | TSHRCA1CA2CA5ACA9 | |
| SCHEMBL1337626 | 0.70 | PTPN1 (0.41) | TDP1KCNH2MAPTSLC6A4 | |
| SCHEMBL10060117 | 0.68 | TSHR (0.50) | TSHRCA1CA2CA5ACA9 | |
| SCHEMBL1338732 | 0.68 | HPGD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063205-B2 | Method for producing 2-oxazoline analogue or 1,3-oxazine analogue | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2011-11-22 | — | — | US | disclosed |
| US-7968751-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7892518-B2 | fluorinating a specific position of a saccharide substrate selectively without affecting a protective group at a temperature within a wide range safely and easily with N, N-diethyl-alpha, alpha-difluoro(3-methyl)benzylamine a fluorinating agent under irradiation with microwave or electromagnetic wave | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-02-22 | — | — | US | disclosed |
| EP-2189467-A2 | Method of fluorination by microwaves | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2189466-A2 | METHOD OF FLUORINATION BY MICROWAVES | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-20090281309-A1 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20080319228-A1 | Method of fluorination | HARA SHOJI | 2008-12-25 | — | — | US | disclosed |
| EP-1956012-A1 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE | National University Corporation Hokkaido University (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20080154064-A1 | Method of fluorination | HARA SHOJI | 2008-06-26 | — | — | US | disclosed |
| US-7351863-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20060014972-A1 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1568703-A1 | METHOD OF FLUORINATION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154064-A1 | Method of fluorination | FUCA2, FABP2, FGB | TSHR 2253/4885CA1 315/4885CA2 1904/4885 |
| US-20080319228-A1 | Method of fluorination | FUCA2, FABP2, FGB | TSHR 2253/4885CA1 315/4885CA2 1904/4885 |
| US-20090281309-A1 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE | OXA1L, SULT1A1, DAO | TSHR 1049/4885CA1 1882/4885CA2 2307/4885 |
| US-20060014972-A1 | Method of fluorination | FUCA2, FABP2, FGB | TSHR 2253/4885CA1 315/4885CA2 1904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.