Sugi Predict

Sugi Predict / Compounds / SCHEMBL295494

SCHEMBL295494

SCHEMBL295494

CCN(CC)C(F)(F)c1cccc(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.40
▸ ACHE P22303 2/20 0.39
▸ KIF11 P52732 4/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ CYP2D6 P10635 2/20 0.39
▸ CYP2C9 P11712 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ KCNH2 Q12809 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ PTPN5 P54829 1/20 0.38
▸ HTT P42858 2/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ CETP P11597 1/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ NFE2L2 Q16236 1/20 0.34
▸ KCNK3 O14649 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14366432 0.84 LMNA (0.39) LMNAACHEKIF11CYP3A4CYP2D6
SCHEMBL19710889 0.79 ACHE (0.41) LMNAACHEKIF11CYP3A4CYP2D6
SCHEMBL812047 0.78 ALDH1A1 (0.44) CYP2D6CYP2C9CYP2C19MEN1KMT2A
SCHEMBL3739351 0.78 LMNA (0.40) LMNAACHEKIF11CYP3A4CYP2D6
SCHEMBL4427051 0.77 KIF11 (0.42) ACHEKIF11CYP3A4KCNH2HPGD
SCHEMBL812665 0.76 TSHR (0.41) ACHEKIF11KCNH2TDP1MAPT
SCHEMBL25875443 0.76 ACHE (0.41) LMNAACHEKIF11CYP3A4CYP2D6
SCHEMBL22671430 0.75 ACHE (0.44) LMNAACHEKIF11CYP3A4CYP2D6
SCHEMBL812199 0.74 ACHE (0.39) LMNAACHEKIF11CYP3A4CYP2D6
SCHEMBL3277997 0.74 ACHE (0.48) LMNAACHEKIF11CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245089-A1 PROCESSES FOR PREPARING TETRALIN COMPOUNDS ARCUS BIOSCIENCES, INC. (US) 2025-11-27 — — WO claimed
EP-2157078-B1 Fluorine compound and fluorinating agent comprising the compound MITSUBISHI GAS CHEMICAL CO (JP) 2012-03-14 — — EP claimed
EP-2157078-A1 Fluorine compound and fluorinating agent comprising the compound Mitsubishi Gas Chemical Company, Inc. (JP) 2010-02-24 — — EP claimed
EP-1422216-B1 FLUORINE COMPOUND AND FLUORINATING AGENT COMPRISING THE COMPOUND MITSUBISHI GAS CHEMICAL CO (JP) 2009-01-07 — — EP claimed
US-7297821-B2 Fluorine compound and fluorinating agent comprising the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-11-20 — — US claimed
US-20060089513-A1 Fluorine compound and fluorinating agent comprising the compound HIDAKA TOSHIO 2006-04-27 — — US claimed
WO-2025245089-A1 PROCESSES FOR PREPARING TETRALIN COMPOUNDS ARCUS BIOSCIENCES, INC. (US) 2025-11-27 — — WO disclosed
US-20250215025-A1 FLUORINE ATOM CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-07-03 — — US disclosed
US-12145901-B1 Process for preparing tetralin compounds ARCUS BIOSCIENCES, INC. (US) 2024-11-19 — — US disclosed
US-12077552-B2 Synthesis of fluoroalkyl tin precursors ENTEGRIS, INC. (US) 2024-09-03 — — US disclosed
EP-4402147-A1 SYNTHESIS OF FLUOROALKYL TIN PRECURSORS Entegris, Inc. (US) 2024-07-24 — — EP disclosed
WO-2024101404-A1 FLUORINE ATOM CONTAINING SILANE COMPOUND ダイキン工業株式会社 2024-05-16 — — WO disclosed
CN-117957235-A Synthesis of fluoroalkyl tin precursors 恩特格里斯公司 2024-04-30 — — CN disclosed
EP-1813596-A1 PROCESS FOR PRODUCING ALPHA, ALPHA- DIFLUOROAMINE National University Corporation Hokkaido University (JP) 2007-08-01 — — EP disclosed
EP-1721885-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROCHEMICAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-11-15 — — EP disclosed
US-20060089513-A1 Fluorine compound and fluorinating agent comprising the compound HIDAKA TOSHIO 2006-04-27 — — US disclosed
US-7019173-B2 Fluorine compound and fluorinating agent comprising the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-03-28 — — US disclosed
US-20060014972-A1 Method of fluorination MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-01-19 — — US disclosed
EP-1568703-A1 METHOD OF FLUORINATION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-08-31 — — EP disclosed
US-20040073065-A1 Fluorine compound and fluorinating agent comprising the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-04-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215025-A1 FLUORINE ATOM CONTAINING SILANE COMPOUND FLI1, AFF1, SF1 LMNA 1513/4885ACHE 3908/4885KIF11 1214/4885
US-12077552-B2 Synthesis of fluoroalkyl tin precursors NISCH, NACA, PNN LMNA 2225/4885ACHE 1263/4885KIF11 1937/4885
US-12145901-B1 Process for preparing tetralin compounds TFPI, TFPI2, F2 LMNA 503/4885ACHE 1989/4885KIF11 908/4885
US-20060089513-A1 Fluorine compound and fluorinating agent comprising the compound AFF1, AFF2, RER1 LMNA 4207/4885ACHE 628/4885KIF11 2339/4885
US-20040073065-A1 Fluorine compound and fluorinating agent comprising the compound AFF1, RER1, AFF2 LMNA 4173/4885ACHE 1008/4885KIF11 2629/4885
US-20060014972-A1 Method of fluorination FUCA2, FABP2, FGB LMNA 745/4885ACHE 3090/4885KIF11 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.