SCHEMBL8143242

SCHEMBL8143242

CCCn1c2ccc(F)cc2c2cc(F)ccc21

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.52
ALDH1A1 P00352 3/20 0.52
HPGD P15428 2/20 0.51
KDM4E B2RXH2 2/20 0.51
LMNA P02545 2/20 0.51
HTT P42858 1/20 0.51
GFER P55789 1/20 0.51
DRD2 P14416 2/20 0.50
SLC6A4 P31645 2/20 0.50
PLK1 P53350 1/20 0.48
PER2 O15055 8/20 0.48
MAPK1 P28482 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CRY2 Q49AN0 9/20 0.45
CRY1 Q16526 7/20 0.45
GAA P10253 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8148630 0.89 MAPT (0.54) MAPTALDH1A1KDM4ELMNADRD2
SCHEMBL16120094 0.84 HPGD (0.57) MAPTALDH1A1HPGDKDM4ELMNA
SCHEMBL8134208 0.83 KDM4E (0.57) MAPTALDH1A1HPGDKDM4EHTT
SCHEMBL9976718 0.83 PSEN1 (0.53) MAPTALDH1A1LMNAPER2MAPK1
SCHEMBL23469449 0.80 MPO (0.49) MAPTALDH1A1KDM4ELMNADRD2
SCHEMBL16120089 0.78 HPGD (0.56) MAPTALDH1A1HPGDKDM4ELMNA
SCHEMBL13304767 0.78 RORA (0.55) MAPTALDH1A1HPGDKDM4ELMNA
SCHEMBL9976729 0.77 RORA (0.51) MAPTALDH1A1LMNAPER2MAPK1
Ammonia Solution, Strong SCHEMBL906134 0.77 HTR6 (0.51) KDM4EHTT
SCHEMBL19885203 0.77 ALDH1A1 (0.48) MAPTALDH1A1LMNAPER2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed