Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PER2 | O15055 | 3/20 | 0.52 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | RORA | P35398 | 4/20 | 0.48 |
| ▸ | RORC | P51449 | 4/20 | 0.48 |
| ▸ | RORB | Q92753 | 4/20 | 0.48 |
| ▸ | ICMT | O60725 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.44 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976718 | 0.90 | PSEN1 (0.53) | MAPTMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL8143242 | 0.89 | MAPT (0.52) | MAPTMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL19885203 | 0.87 | ALDH1A1 (0.48) | MAPTMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL23469449 | 0.84 | MPO (0.49) | MAPTMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL9976729 | 0.83 | RORA (0.51) | MAPTMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL14141830 | 0.83 | RORA (0.73) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL8134208 | 0.80 | KDM4E (0.57) | MAPTMAPK1ALDH1A1GAAPER2 | |
| SCHEMBL31609292 | 0.80 | PER2 (0.48) | MAPTMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL29623057 | 0.80 | PER2 (0.51) | MAPTMAPK1ALDH1A1SMN1; SMN2PER2 | |
| SCHEMBL12374352 | 0.79 | RORA (0.69) | ALDH1A1GAASMN1; SMN2PGRRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034206-A | POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE | TOSOH CORPORATION (JP) | 2000-03-07 | — | — | US | disclosed |