Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18285261 | 0.87 | — | — | |
| SCHEMBL20243067 | 0.86 | FAAH (0.34) | ALDH1A1ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL2123553 | 0.83 | GPR55 (0.39) | ALDH1A1SMN1; SMN2MAPK1MAPTLMNA | |
| SCHEMBL28148610 | 0.77 | NOTUM (0.35) | ALDH1A1KMT2ASMN1; SMN2FAAHMGLL | |
| SCHEMBL18069699 | 0.76 | RAB9A (0.40) | ALDH1A1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19629453 | 0.73 | NOTUM (0.41) | ALDH1A1SMN1; SMN2MAPK1MGLLMAPT | |
| SCHEMBL979154 | 0.71 | CYP2C19 (0.41) | ALDH1A1KMT2ACYP2C19SMN1; SMN2MAPT | |
| SCHEMBL10525605 | 0.70 | ITGB2 (0.39) | ALDH1A1ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL25077928 | 0.69 | LMNA (0.48) | ALDH1A1KMT2ACYP2C19SMN1; SMN2MGLL | |
| SCHEMBL23647722 | 0.67 | ALDH1A1 (0.48) | ALDH1A1KMT2AMGLLMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217415-B | Method for synthesizing chiral 3-amino-1-phenylpropanol and chiral 3- (methylamino) -1-phenylpropanol | 武汉大学 | 2024-06-18 | — | — | CN | claimed |
| CN-115385877-B | Dihydrofuran-2-one compound and preparation method thereof | 嘉兴学院 | 2024-02-23 | — | — | CN | claimed |
| CN-116217415-A | Method for synthesizing chiral 3-amino-1-phenylpropanol and chiral 3- (methylamino) -1-phenylpropanol | 武汉大学 | 2023-06-06 | — | — | CN | claimed |
| CN-115385877-A | Dihydrofuran-2-ketone compound and preparation method thereof | 嘉兴学院 | 2022-11-25 | — | — | CN | claimed |
| US-5763627-A | Process for preparing cyclopropyl alkyl ketones and 4,5-dihydroalkyfurans | HUELS AKTIENGESELLSCHAFT (DE) | 1998-06-09 | — | — | US | claimed |
| CN-116217415-B | Method for synthesizing chiral 3-amino-1-phenylpropanol and chiral 3- (methylamino) -1-phenylpropanol | 武汉大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-115385877-B | Dihydrofuran-2-one compound and preparation method thereof | 嘉兴学院 | 2024-02-23 | — | — | CN | disclosed |
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | SUNDANCE BIOSCIENCES, INC. | 2024-01-25 | — | — | US | disclosed |
| CN-116217415-A | Method for synthesizing chiral 3-amino-1-phenylpropanol and chiral 3- (methylamino) -1-phenylpropanol | 武汉大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-115385877-A | Dihydrofuran-2-ketone compound and preparation method thereof | 嘉兴学院 | 2022-11-25 | — | — | CN | disclosed |
| CN-107699917-B | A kind of method of electrochemistry formated lactone | 南阳师范学院 | 2019-02-15 | — | — | CN | disclosed |
| CN-107699917-A | A kind of method of electrochemistry formated lactone | 南阳师范学院 | 2018-02-16 | — | — | CN | disclosed |
| US-20160263565-A1 | RUTHENIUM-CATALYZED SYNTHESIS OF BIARYL COMPOUNDS IN WATER | CHICAGO DISCOVERY SOLUTIONS, LLC (US) | 2016-09-15 | — | — | US | disclosed |
| US-20070299052-A1 | Inhibitors of IAP | GENENTECH, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| EP-0820977-B1 | Process for the preparation of cyclopropylalkylketones and 4,5-dihydroalkylfurans | DEGUSSA (DE) | 2000-04-26 | — | — | EP | disclosed |
| US-5763627-A | Process for preparing cyclopropyl alkyl ketones and 4,5-dihydroalkyfurans | HUELS AKTIENGESELLSCHAFT (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0820977-A1 | Process for the preparation of cyclopropylalkylketones and 4,5-dihydroalkylfurans | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-01-28 | — | — | EP | disclosed |
| EP-0725066-B1 | Process for the production of cyclopropylalkylketones and 4,5-dihydroalkylfuranes | HUELS CHEMISCHE WERKE AG (DE) | 1997-07-16 | — | — | EP | disclosed |
| US-5629455-A | Process for preparing cyclopropyl alkyl ketones and 4,5-dihydroalkylfurans | HUELS AKTIENGESELLSCHAFT (DE) | 1997-05-13 | — | — | US | disclosed |
| EP-0725066-A1 | Process for the production of cyclopropylalkylketones and 4,5-dihydroalkylfuranes | HÜLS AKTIENGESELLSCHAFT (DE) | 1996-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299052-A1 | Inhibitors of IAP | XIAP, BIRC5, BIRC3 | ALDH1A1 4132/4885ITGB2 4630/4885ICAM1 1464/4885 |
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | TYK2, JAK1, JAK3 | ALDH1A1 4807/4885ITGB2 3965/4885ICAM1 3085/4885 |
| US-20160263565-A1 | RUTHENIUM-CATALYZED SYNTHESIS OF BIARYL COMPOUNDS IN WATER | RUVBL2, RUVBL1, CYP2W1 | ALDH1A1 2208/4885ITGB2 1697/4885ICAM1 4305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.