SCHEMBL815947

SCHEMBL815947

C=CC(=O)OCCCCCCOc1ccc2cc(C(=O)Oc3ccc(OC(=O)c4ccc5cc(OC(=O)C=C)ccc5c4)c(CCC)c3)ccc2c1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.42
THRA P10827 2/20 0.41
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PPARG P37231 2/20 0.37
PPARD Q03181 2/20 0.37
PPARA Q07869 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL816412 1.00 THRB (0.42) THRBTHRAHPGDTSHRNFKB1
SCHEMBL19757256 1.00 THRB (0.42) THRBTHRAHPGDTSHRNFKB1
SCHEMBL815712 0.99 THRB (0.41) THRBTHRAHPGDTSHRNFKB1
SCHEMBL15398098 0.98 THRB (0.41) THRBTHRAHPGDTSHRNFKB1
SCHEMBL816972 0.98 THRB (0.43) THRBTHRAHPGDTSHRNFKB1
SCHEMBL12733661 0.98 THRB (0.41) THRBTHRAHPGDTSHRNFKB1
SCHEMBL12975846 0.97 THRB (0.40) THRBTHRAHPGDTSHRNFKB1
SCHEMBL12141963 0.97 THRB (0.41) THRBTHRAHPGDTSHRNFKB1
SCHEMBL816326 0.96 THRB (0.39) THRBTHRAHPGDTSHRPPARG
SCHEMBL21663507 0.96 THRA (0.40) THRBTHRAHPGDTSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370740-B2 Method for producing ester group-containing compound DIC CORPORATION (JP) 2022-06-28 US disclosed
EP-3438134-B1 POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT ADEKA CORP (JP) 2021-05-05 EP disclosed
US-10723952-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2020-07-28 US disclosed
US-10647662-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2020-05-12 US disclosed
EP-2695930-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE, NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE DAINIPPON INK & CHEMICALS (JP) 2019-09-11 EP disclosed
EP-2261201-B1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND DAINIPPON INK & CHEMICALS (JP) 2018-05-30 EP disclosed
US-20180002276-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2018-01-04 US disclosed
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-10-26 US disclosed
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-10-26 US disclosed
US-20170073581-A1 MIXTURE THAT INCLUDES COMPOUND CONTAINING MESOGENIC GROUP DIC CORPORATION (JP) 2017-03-16 US disclosed
US-7910021-B2 Polymerizable optical active compound and polymerizable composition containing the same ADEKA CORPORATION (JP) 2011-03-22 US disclosed
US-20110037025-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME ADEKA CORPORATION (JP) 2011-02-17 US disclosed
US-20110037025-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME ADEKA CORPORATION (JP) 2011-02-17 US disclosed
US-20100328601-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY USING THE LIQUID CRYSTAL COMPOSITION ADEKA CORPORATION (JP) 2010-12-30 US disclosed
US-20100328601-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY USING THE LIQUID CRYSTAL COMPOSITION ADEKA CORPORATION (JP) 2010-12-30 US disclosed
EP-2261201-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND Adeka Corporation (JP) 2010-12-15 EP disclosed
EP-2243813-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL DISPLAY ELEMENT COMPRISING THE LIQUID CRYSTAL COMPOSITION Adeka Corporation (JP) 2010-10-27 EP disclosed
US-7754912-B2 acrylate compound as intermediate for a liquid crystal polymer ADEKA CORPORATION (JP) 2010-07-13 US disclosed
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME ADEKA CORPORATION (JP) 2010-02-11 US disclosed
US-20090247782-A1 NOVEL POLYMERIZABLE COMPOUNDS ADEKA CORPORATION (JP) 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11370740-B2 Method for producing ester group-containing compound COASY, TAF5, TAF9 THRB 4843/4885THRA 4791/4885HPGD 1044/4885
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME C1S, PYM1, MCCC2 THRB 3247/4885THRA 2790/4885HPGD 4696/4885
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY SMC4, PHOSPHO1, SMCHD1 THRB 4883/4885THRA 4853/4885HPGD 4408/4885
US-10647662-B2 Polymerizable compound and optically anisotropic body RCC1, SMC4, SMCHD1 THRB 4796/4885THRA 4729/4885HPGD 4355/4885
US-20110037025-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME PYM1, MT-CO1, MAT1A THRB 341/4885THRA 426/4885HPGD 3793/4885
US-20180002276-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY RCC1, SMC4, SMCHD1 THRB 4796/4885THRA 4729/4885HPGD 4355/4885
US-20090247782-A1 NOVEL POLYMERIZABLE COMPOUNDS CCNT1, CCNE2, MYB THRB 3445/4885THRA 2438/4885HPGD 606/4885
US-10723952-B2 Polymerizable compound and optically anisotropic body SMC4, SMCHD1, PHOSPHO1 THRB 4884/4885THRA 4864/4885HPGD 4404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.