SCHEMBL816306

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27250293	0.83	KIF11 (0.51)	KIF11CA5ARXRARXRBRXRG
	SCHEMBL817538	0.80	RXRA (0.46)	CA5ARXRARXRBRXRGLMNA
	SCHEMBL13749764	0.78	ERN1 (0.41)	MAOBCES2
	SCHEMBL816784	0.78	CES2 (0.35)	KIF11RXRARXRBRXRGLMNA
	SCHEMBL28652802	0.78	KIF11 (0.51)	KIF11CA5ARXRARXRBRXRG
	SCHEMBL816310	0.78	NOTUM (0.57)	LMNANOTUM
	SCHEMBL1925084	0.77	KIF11 (0.59)	KIF11RXRARXRBRXRGAKR1C3
	SCHEMBL30440617	0.76	NPFFR2 (0.58)	KIF11NPFFR2LMNANOTUMKDR
	SCHEMBL17407194	0.76	KIF11 (0.50)	KIF11CA5ARXRARXRBRXRG
	SCHEMBL76697	0.76	NPFFR2 (0.58)	KIF11NPFFR2LMNANOTUMKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.