Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950882 | 0.82 | TRPA1 (0.48) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL6515010 | 0.81 | TRPA1 (0.52) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL29407046 | 0.80 | TRPA1 (0.46) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL697259 | 0.80 | ESR1 (0.50) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL715998 | 0.80 | TRPA1 (0.46) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL31519420 | 0.80 | ESR1 (0.50) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL81004 | 0.80 | TRPA1 (0.46) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL19158691 | 0.80 | TRPA1 (0.46) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL23969500 | 0.78 | TRPA1 (0.44) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL16952249 | 0.78 | TRPA1 (0.44) | TRPA1ATMESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029278-A2 | CONJUGATES OF ANTITHROMBIN BINDING OLIGOSACCHARIDE DERIVATIVES AND THERAPEUTIC PROTEINS | ENDOTIS PHARMA S.A. (FR) | 2008-03-13 | — | — | WO | claimed |
| EP-1886696-A1 | Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins | Endotis Pharma (FR) | 2008-02-13 | — | — | EP | claimed |
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135350-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | claimed |
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | claimed |
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | claimed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | claimed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | claimed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | claimed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | claimed |
| WO-1994022911-A2 | A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING Nα-METHYLARGININE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-13 | — | — | WO | claimed |
| US-11931415-B2 | Ophthalmic compositions | THE UNIVERSITY OF LIVERPOOL (GB) | 2024-03-19 | — | — | US | disclosed |
| CN-117388491-A | SVA neutralizing antibody liquid phase blocking ELISA detection kit | 中国农业科学院兰州兽医研究所 | 2024-01-12 | — | — | CN | disclosed |
| EP-3496760-B1 | OPHTHALMIC COMPOSITIONS | UNIV LIVERPOOL (GB) | 2022-02-09 | — | — | EP | disclosed |
| US-20210220335-A1 | NITROIMIDAZOLE FORMULATIONS | IRP Health Pty Ltd (AU) | 2021-07-22 | — | — | US | disclosed |
| WO-1994022911-A2 | A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING Nα-METHYLARGININE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-13 | — | — | WO | disclosed |
| US-5179066-A | THERMOSENSITIVE RECORDING MATERIAL | YAMADA CHEMICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| US-4737297-A | MONO-SUBSTITUTED NAPHTHALENES | NIPPON OIL CO., LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| US-4665275-A | OXIDATION-RESISTANT NAPHTHALENE DERIVATIVE | NIPPON OIL CO., LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220335-A1 | NITROIMIDAZOLE FORMULATIONS | PHB1, COX5B, CYP3A5 | TRPA1 3573/4885ATM 3764/4885ESR1 4380/4885 |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | TRPA1 1912/4885ATM 3933/4885ESR1 1108/4885 |
| US-11931415-B2 | Ophthalmic compositions | CRYAB, CRYAA, PDE6D | TRPA1 424/4885ATM 758/4885ESR1 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.