Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.44 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161075 | 0.92 | LMNA (0.48) | RAB9ASMN1; SMN2USP28USP25LMNA | |
| SCHEMBL8807401 | 0.91 | LMNA (0.45) | USP28USP25LMNAHTTMTNR1B | |
| SCHEMBL8808890 | 0.89 | MTNR1B (0.45) | USP28USP25LMNAHTTMTNR1B | |
| SCHEMBL1907786 | 0.88 | RXRA (0.53) | RAB9AUSP28USP25LMNAPTGER1 | |
| SCHEMBL8167573 | 0.88 | LMNA (0.55) | SMN1; SMN2LMNAHTTPTGER1CYP1A2 | |
| SCHEMBL7662467 | 0.87 | CCR5 (0.45) | RAB9ASMN1; SMN2USP28USP25LMNA | |
| SCHEMBL8155064 | 0.86 | PTGER1 (0.41) | RAB9AUSP28USP25LMNAHTT | |
| SCHEMBL8167295 | 0.86 | PTGER1 (0.46) | RAB9AUSP28USP25LMNAHTT | |
| SCHEMBL8167536 | 0.86 | USP28 (0.46) | RAB9AUSP28USP25LMNAHTT | |
| SCHEMBL8154577 | 0.86 | GPR132 (0.46) | RAB9AUSP28USP25LMNAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773930-B1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LTD (GB) | 2000-10-11 | — | — | EP | disclosed |
| US-5843942-A | Aromatic amino ethers as pain relieving agents | ZENECA LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |
| EP-0773930-A1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LIMITED (GB) | 1997-05-21 | — | — | EP | disclosed |