Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560464 | 0.96 | C3AR1 (0.39) | C3AR1TPSAB1CYP1A2CYP2D6PKM | |
| SCHEMBL8174677 | 0.91 | TPSAB1 (0.39) | TPSAB1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL8169663 | 0.79 | LMNA (0.37) | C3AR1ITGB3ITGA2BNAAAHDAC7 | |
| SCHEMBL3928059 | 0.74 | SLC7A5 (0.40) | NAAASMN1; SMN2 | |
| SCHEMBL6723179 | 0.73 | ALDH1A1 (0.40) | NAAASMN1; SMN2 | |
| SCHEMBL6716961 | 0.73 | ALDH1A1 (0.40) | NAAASMN1; SMN2 | |
| SCHEMBL29288010 | 0.72 | KDM1A (0.40) | NAAAKDM1AMAOBCYP1A2SMN1; SMN2 | |
| SCHEMBL6003373 | 0.72 | POLB (0.42) | NAAASMN1; SMN2 | |
| SCHEMBL8557724 | 0.72 | ALOX15 (0.37) | CYP1A2SMN1; SMN2DPP7 | |
| SCHEMBL9030495 | 0.71 | F2 (0.53) | ITGB3ITGA2BTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |