Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.33 |
| ▸ | GALR1 | P47211 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209525 | 0.88 | KMT2A (0.37) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL8207229 | 0.87 | ALOX15 (0.40) | KMT2AGAAMAPTGFERALDH1A1 | |
| SCHEMBL8211806 | 0.86 | PYGL (0.36) | KMT2AMEN1GAAMAPTGFER | |
| SCHEMBL8212891 | 0.86 | ALDH1A1 (0.40) | KMT2AMEN1GAAMAPTGFER | |
| SCHEMBL8200315 | 0.85 | ALOX15 (0.40) | KMT2AALDH1A1ALOX15SMN1; SMN2HPGD | |
| SCHEMBL8200038 | 0.84 | NPC1 (0.37) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL8198895 | 0.82 | SMN1; SMN2 (0.38) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL8206432 | 0.74 | TAAR1 (0.54) | TAAR1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8212479 | 0.74 | MAPT (0.38) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL8207755 | 0.73 | GRIN2C (0.48) | NPC1RAB9AKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |