Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212891 | 0.92 | ALDH1A1 (0.40) | ALOX15HSD17B10GAAMAPK1MAPT | |
| SCHEMBL8200315 | 0.92 | ALOX15 (0.40) | ALOX15TP53GALR1ALDH1A1KMT2A | |
| SCHEMBL8209525 | 0.89 | KMT2A (0.37) | ALOX15HSD17B10GAAMAPTHTT | |
| SCHEMBL8199872 | 0.87 | TAAR1 (0.44) | ALOX15GAAMAPTHTTGALR1 | |
| SCHEMBL8211806 | 0.87 | PYGL (0.36) | LMNAGAAMAPTHTTALDH1A1 | |
| SCHEMBL8207755 | 0.83 | GRIN2C (0.48) | GAAMAPTNPSR1HTTALDH1A1 | |
| SCHEMBL8200396 | 0.81 | ALDH1A1 (0.44) | HSD17B10GAAMAPK1MAPTNPSR1 | |
| SCHEMBL8200330 | 0.81 | MAPT (0.45) | LMNAGAAMAPTNPSR1HTT | |
| SCHEMBL8200017 | 0.79 | MAPT (0.46) | LMNAGAAMAPTNPSR1HTT | |
| SCHEMBL8206045 | 0.76 | GRIN2C (0.39) | MAPTHTTGALR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |