Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207229 | 0.89 | ALOX15 (0.40) | KMT2AMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8199872 | 0.88 | TAAR1 (0.44) | KMT2AMAPTALDH1A1ALOX15GAA | |
| SCHEMBL8211806 | 0.88 | PYGL (0.36) | KMT2AMAPTALDH1A1GAAGFER | |
| SCHEMBL8212891 | 0.87 | ALDH1A1 (0.40) | KMT2AMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8200315 | 0.87 | ALOX15 (0.40) | KMT2AALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL8212479 | 0.83 | MAPT (0.38) | KMT2AMAPTALDH1A1GAAHPGDS | |
| SCHEMBL8210397 | 0.81 | KDM4E (0.41) | KMT2AMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL7881616 | 0.80 | LMNA (0.36) | KMT2AMAPTGAASMN1; SMN2POLB | |
| SCHEMBL8200147 | 0.78 | REV1 (0.38) | KMT2AMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8206432 | 0.76 | TAAR1 (0.54) | KMT2AMAPTALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |