Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 7/20 | 0.37 |
| ▸ | NPY1R | P25929 | 5/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | NRP1 | O14786 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218389 | 0.88 | NOD1 (0.46) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7218393 | 0.88 | NOD1 (0.46) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7227064 | 0.81 | NOD1 (0.50) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7227075 | 0.81 | NOD1 (0.50) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL8193777 | 0.81 | DPP7 (0.43) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL8224459 | 0.77 | SIRT6 (0.40) | NOD1SIRT6SIRT1POLBKMT2A | |
| SCHEMBL8080773 | 0.77 | GNAI3 (0.46) | NOD1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL8201903 | 0.76 | KMT2A (0.49) | NOD1SIRT6SIRT1POLBKMT2A | |
| SCHEMBL8193137 | 0.76 | SIRT1 (0.39) | NOD1SIRT6SIRT1POLBKMT2A | |
| SCHEMBL8206011 | 0.75 | DRD1 (0.46) | SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885188-B1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2000-09-27 | — | — | EP | claimed |