Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909709 | 0.87 | SLC6A5 (0.51) | NOD1SIRT6SIRT1SLC6A5NMT2 | |
| SCHEMBL7225493 | 0.87 | SLC6A5 (0.51) | NOD1SIRT6SIRT1SLC6A5NMT2 | |
| SCHEMBL8224459 | 0.85 | SIRT6 (0.40) | KMT2APOLBNOD1L3MBTL1SIRT6 | |
| SCHEMBL8193137 | 0.84 | SIRT1 (0.39) | KMT2APOLBNOD1L3MBTL1SIRT6 | |
| SCHEMBL8193831 | 0.78 | CYP1A2 (0.50) | KMT2APOLBCYP1A2 | |
| SCHEMBL8201070 | 0.76 | NOD1 (0.39) | KMT2APOLBNOD1SIRT6SIRT1 | |
| SCHEMBL2436856 | 0.76 | NOD1 (0.65) | KMT2APOLBNOD1L3MBTL1SIRT6 | |
| SCHEMBL3167324 | 0.76 | NOD1 (0.65) | KMT2APOLBNOD1L3MBTL1SIRT6 | |
| SCHEMBL8193777 | 0.76 | DPP7 (0.43) | NOD1 | |
| Hydrochloric Acid SCHEMBL4931989 | 0.75 | NOD1 (0.63) | KMT2APOLBNOD1L3MBTL1SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885188-B1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2000-09-27 | — | — | EP | claimed |