Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206395 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL8199503 | 0.79 | CA2 (0.46) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8205571 | 0.76 | ADRA2A (0.50) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL9662609 | 0.70 | ADRA2A (0.38) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL570524 | 0.69 | ADRA2A (0.47) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL5350083 | 0.69 | FPR2 (0.52) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL7711870 | 0.68 | TBXA2R (0.45) | KDM4E | |
| Benzoic Acid SCHEMBL27988244 | 0.68 | ALDH1A1 (0.57) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28220351 | 0.67 | ADRA2A (0.46) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| Bromide SCHEMBL28219788 | 0.67 | ADRA2A (0.46) | ALDH1A1KDM4EADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |