Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CRHBP | P24387 | 2/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820893 | 0.78 | CYP3A4 (0.44) | L3MBTL1ALDH1A1MAPTMAPK1CYP1A2 | |
| SCHEMBL13377362 | 0.74 | GABRA1 (0.38) | L3MBTL1ALDH1A1KMT2AMAPTCYP1A2 | |
| SCHEMBL310828 | 0.73 | ALDH1A1 (0.83) | L3MBTL1ALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL8986915 | 0.73 | ALDH1A1 (0.83) | L3MBTL1ALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL9821485 | 0.70 | ALDH1A1 (0.78) | L3MBTL1ALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL3853529 | 0.69 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL17817838 | 0.69 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL1039452 | 0.69 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL31155753 | 0.69 | ATM (0.48) | L3MBTL1ALDH1A1MEN1KMT2ACRHBP | |
| SCHEMBL13902996 | 0.69 | TDP1 (0.50) | L3MBTL1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275783-A1 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | claimed |
| US-20110275781-A1 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | claimed |
| US-8492508-B2 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2013-07-23 | — | — | US | disclosed |
| US-8367797-B2 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2013-02-05 | — | — | US | disclosed |
| US-20110275783-A1 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | disclosed |
| US-20110275781-A1 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275783-A1 | Nitro compound, amine compound and polyamide derived therefrom | NOS2, NOS1, NOS3 | L3MBTL1 3661/4885ALDH1A1 2358/4885MEN1 3790/4885 |
| US-20110275781-A1 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | THEM6, NOS2, NOS1 | L3MBTL1 4279/4885ALDH1A1 2644/4885MEN1 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.