Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21748449 | 0.74 | NFKB1 (0.40) | NFKB1 | |
| SCHEMBL8666930 | 0.72 | — | — | |
| SCHEMBL8666193 | 0.72 | — | — | |
| SCHEMBL29674792 | 0.72 | — | — | |
| Potassium Ion SCHEMBL2002335 | 0.71 | NFKB1 (0.38) | NFKB1 | |
| Tetramethylammonium Ion SCHEMBL2298162 | 0.68 | NFKB1 (0.30) | NFKB1 | |
| SCHEMBL19039716 | 0.67 | NFKB1 (0.40) | NFKB1 | |
| SCHEMBL199775 | 0.67 | NFKB1 (0.40) | NFKB1 | |
| SCHEMBL896776 | 0.67 | — | — | |
| SCHEMBL1606223 | 0.67 | DNM1 (0.36) | NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705864-B1 | Method of emulsion polymerization | DOW CORNING (US) | 2000-03-01 | — | — | EP | disclosed |
| EP-0705864-A1 | Method of emulsion polymerization | DOW CORNING CORPORATION (US) | 1996-04-10 | — | — | EP | disclosed |