Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415763 | 0.79 | MAPT (0.47) | KEAP1SLC9A1MAPTHTTKMT2A | |
| SCHEMBL12523116 | 0.79 | NPC1 (0.47) | KEAP1SLC9A1MAPTHTTHSD17B10 | |
| SCHEMBL11140112 | 0.78 | KEAP1 (0.44) | KEAP1SLC9A1MAPTHTTHSD17B10 | |
| SCHEMBL17844431 | 0.78 | NPC1 (0.42) | KEAP1SLC9A1MAPTHTTHSD17B10 | |
| SCHEMBL13344636 | 0.78 | KEAP1 (0.44) | KEAP1SLC9A1MAPTHTTHSD17B10 | |
| SCHEMBL8659186 | 0.77 | NPC1 (0.44) | MAPTHTTMAPK1KMT2ANSD3 | |
| SCHEMBL15958641 | 0.76 | KDM4E (0.45) | KEAP1SLC9A1MAPTHTTHSD17B10 | |
| SCHEMBL458167 | 0.75 | ALDH1A1 (0.45) | MAPTHTTMEN1MAPK1KMT2A | |
| SCHEMBL28097914 | 0.75 | POLB (0.45) | MAPTHTTMEN1MAPK1KMT2A | |
| SCHEMBL19449451 | 0.75 | SMN1; SMN2 (0.45) | KMT2ANSD3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189050-B1 | ANTIVIRAL AGENTS AND USES THEREOF | UNIV GRIFFITH (AU) | 2020-02-05 | — | — | EP | disclosed |
| EP-2590967-B1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | UDC IRELAND LTD (IE) | 2019-05-15 | — | — | EP | disclosed |
| US-20170290809-A1 | ANTIVIRAL AGENTS AND USES THEREOF | GRIFFITH UNIVERSITY (AU) | 2017-10-12 | — | — | US | disclosed |
| US-9447245-B2 | Cross-linking and stabilization of organic metal complexes in networks | CYNORA GMBH (DE) | 2016-09-20 | — | — | US | disclosed |
| US-9447246-B2 | Method of covalently bonding an organic metal complex to a polymer | CYNORA GMBH (DE) | 2016-09-20 | — | — | US | disclosed |
| US-9067919-B2 | Use of dibenzofurans and dibenzothiophenes substituted by nitrogen-bonded five-membered heterocyclic rings in organic electronics | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20140142258-A1 | CROSS-LINKING AND STABILIZATION OF ORGANIC METAL COMPLEXES IN NETWORKS | CYNORA GMBH (DE) | 2014-05-22 | — | — | US | disclosed |
| US-20140142259-A1 | METHOD OF COVALENTLY BONDING AN ORGANIC METAL COMPLEX TO A POLYMER | CYNORA GMBH (DE) | 2014-05-22 | — | — | US | disclosed |
| US-20120007063-A1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | BASF SE (DE) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142259-A1 | METHOD OF COVALENTLY BONDING AN ORGANIC METAL COMPLEX TO A POLYMER | PICALM, LIG4, OSTC | KEAP1 805/4885SLC9A1 4390/4885MAPT 849/4885 |
| US-20170290809-A1 | ANTIVIRAL AGENTS AND USES THEREOF | RNASE1, ENTPD5, ACE | KEAP1 4043/4885SLC9A1 3365/4885MAPT 4843/4885 |
| US-20120007063-A1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | DDT, DBF4, POU5F1 | KEAP1 1196/4885SLC9A1 1148/4885MAPT 2127/4885 |
| US-20140142258-A1 | CROSS-LINKING AND STABILIZATION OF ORGANIC METAL COMPLEXES IN NETWORKS | SOD1, MTCL3, LIG4 | KEAP1 967/4885SLC9A1 4463/4885MAPT 494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.