Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452483 | 0.87 | ACLY (0.53) | SMN1; SMN2ALDH1A1TSHRPOLBHTT | |
| SCHEMBL22580263 | 0.85 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1TSHRPOLBHTT | |
| SCHEMBL2318648 | 0.84 | HPGDS (0.51) | SMN1; SMN2ALDH1A1TSHRPOLBHTT | |
| SCHEMBL5966721 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1TSHRHTTKMT2A | |
| SCHEMBL12377870 | 0.82 | L3MBTL1 (0.62) | SMN1; SMN2ALDH1A1TSHRHTTKMT2A | |
| SCHEMBL4604449 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1TSHRPOLBHTT | |
| SCHEMBL22322904 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1POLBKMT2ALMNA | |
| SCHEMBL3375138 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL420682 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1TSHRHTTKMT2A | |
| SCHEMBL13028853 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1TSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814702-B | Curable organosilicon composition and optical semiconductor device | 道康宁东丽株式会社 | 2018-06-26 | — | — | CN | claimed |
| US-9691951-B2 | Curable silicone composition, and optical semiconductor device | DOW CORNING TORAY CO., LTD. (JP) | 2017-06-27 | — | — | US | claimed |
| EP-3059768-A1 | CURABLE SILICONE COMPOSITION, AND OPTICAL SEMICONDUCTOR DEVICE | Dow Corning Toray Co., Ltd. (JP) | 2016-08-24 | — | — | EP | claimed |
| US-20160233395-A1 | Curable Silicone Composition, And Optical Semiconductor Device | DOW TORAY CO., LTD. (JP) | 2016-08-11 | — | — | US | claimed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | claimed |
| US-20240002355-A1 | PROCESS FOR THE MANUFACTURE OF TETRAZOLE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2024-01-04 | — | — | US | disclosed |
| US-20230321091-A1 | SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | EDGEWISE THERAPEUTICS, INC. | 2023-10-12 | — | — | US | disclosed |
| EP-4248973-A2 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116635372-A | Novel process for producing tetrazole derivatives | 豪夫迈·罗氏有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022106669-A1 | NEW PROCESS FOR THE MANUFACTURE OF TETRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-05-27 | — | — | WO | disclosed |
| WO-2021231615-A1 | SUBSTITUTED PYRIDAZINONE FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | EDGEWISE THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
| EP-3227018-B1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | UNIV VIRGINIA COMMONWEALTH (US) | 2021-06-30 | — | — | EP | disclosed |
| EP-0297042-A1 | Substituted penem compounds | CIBA-GEIGY AG (CH) | 1988-12-28 | — | — | EP | disclosed |
| EP-0233155-A1 | Aminoacyloxymethyl compounds | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| EP-0215739-A1 | Synthesis of beta-lactam compounds | CIBA-GEIGY AG (CH) | 1987-03-25 | — | — | EP | disclosed |
| EP-0201459-A1 | Acylaminomethyl-penem compounds, their preparation and pharmaceutical formulations containing them | CIBA-GEIGY AG (CH) | 1986-11-12 | — | — | EP | disclosed |
| EP-0132165-A1 | Adsorbable alkynyl substituted heterocyclic quaternary ammonium salts and applications thereof to silver halide photography | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-01-23 | — | — | EP | disclosed |
| US-4471044-A | Silver halide emulsions and photographic elements containing adsorbable alkynyl substituted heterocyclic quaternary ammonium salts | EASTMAN KODAK COMPANY (US) | 1984-09-11 | — | — | US | disclosed |
| US-4115122-A | Internal latent image silver halide emulsion containing a heterocyclic quaternary salt having a propargyl or a butyryl containing substituent | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321091-A1 | SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | IL6, MUSK, SMN1; SMN2 | SMN1; SMN2 3/4885ALDH1A1 308/4885TSHR 3553/4885 |
| US-20240002355-A1 | PROCESS FOR THE MANUFACTURE OF TETRAZOLE DERIVATIVES | CYP2F1, CYP1A2, CYP3A4 | SMN1; SMN2 2234/4885ALDH1A1 173/4885TSHR 162/4885 |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | SMN1; SMN2 3894/4885ALDH1A1 2972/4885TSHR 4292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.