SCHEMBL823219

SCHEMBL823219

O=C(O)c1ccc2c3ccc(C(=O)NCCc4ccccc4)c4c(C(=O)O)ccc(c5ccc(C(=O)NCCc6ccccc6)c1c25)c43

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.56
NPC1 O15118 7/20 0.56
LMNA P02545 1/20 0.56
MAPT P10636 1/20 0.56
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
EGLN1 Q9GZT9 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP3 P08254 1/20 0.49
CA9 Q16790 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5187348 1.00 RAB9A (0.56) RAB9ANPC1LMNAMAPTKDM4E
SCHEMBL16351643 1.00 RAB9A (0.56) RAB9ANPC1LMNAMAPTKDM4E
SCHEMBL5051133 0.95 KMT2A (0.56) RAB9ANPC1LMNAMAPTKDM4E
SCHEMBL16351644 0.95 KMT2A (0.56) RAB9ANPC1LMNAMAPTKDM4E
SCHEMBL16352053 0.94 RAB9A (0.62) RAB9ANPC1LMNAMAPTALDH1A1
SCHEMBL822668 0.94 RAB9A (0.62) RAB9ANPC1LMNAMAPTALDH1A1
SCHEMBL3796253 0.94 RAB9A (0.62) RAB9ANPC1LMNAMAPTALDH1A1
SCHEMBL29705135 0.92 EGLN1 (0.49) RAB9ANPC1LMNAMAPTKDM4E
SCHEMBL12038225 0.90 MAPT (0.47) RAB9ANPC1LMNAMAPTKDM4E
SCHEMBL16351306 0.90 PLAAT3 (0.48) RAB9ANPC1LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 US disclosed
US-8431433-B2 Methods of providing semiconductor layers from amic acid salts EASTMAN KODAK COMPANY (US) 2013-04-30 US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC RAB9A 2482/4885NPC1 2148/4885LMNA 1018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.