Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236014 | 0.82 | MAPT (0.50) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5320148 | 0.80 | ALDH1A1 (0.54) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5338305 | 0.80 | MAPT (0.48) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28428243 | 0.75 | ADORA3 (0.56) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL5334907 | 0.74 | GSK3B (0.43) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8227750 | 0.73 | MAPT (0.46) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8233961 | 0.73 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL8038965 | 0.73 | TMIGD3 (0.50) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL28428248 | 0.72 | MEN1 (0.51) | MAPTGAASMN1; SMN2LMNAMEN1 | |
| SCHEMBL8236528 | 0.71 | CXCR3 (0.41) | MAPTGAAALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |