SCHEMBL823563

SCHEMBL823563

O=C(CCCCCNC(=O)c1ccccc1S)Nc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 20/20 0.65
HDAC1 Q13547 20/20 0.65
HDAC7 Q8WUI4 20/20 0.65
HDAC11 Q96DB2 20/20 0.65
HDAC8 Q9BY41 20/20 0.65
HDAC6 Q9UBN7 20/20 0.65
HDAC9 Q9UKV0 20/20 0.65
HDAC5 Q9UQL6 20/20 0.65
HDAC3 O15379 19/20 0.65
HDAC2 Q92769 19/20 0.65
HDAC10 Q969S8 19/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL823655 1.00 HDAC4 (0.65) HDAC4HDAC1HDAC7HDAC11HDAC8
SCHEMBL823656 1.00 HDAC4 (0.65) HDAC4HDAC1HDAC7HDAC11HDAC8
SCHEMBL823555 1.00 HDAC4 (0.65) HDAC4HDAC1HDAC7HDAC11HDAC8
SCHEMBL823560 0.90 HDAC3 (0.54) HDAC4HDAC1HDAC7HDAC11HDAC8
SCHEMBL823591 0.87 HDAC3 (0.61) HDAC4HDAC1HDAC7HDAC11HDAC8
SCHEMBL823581 0.87 HDAC3 (0.59) HDAC4HDAC1HDAC7HDAC11HDAC8
SCHEMBL823597 0.86 HDAC3 (0.57) HDAC4HDAC1HDAC7HDAC11HDAC8
SCHEMBL823548 0.84 ALOX5 (0.59) HDAC4HDAC1HDAC7HDAC11HDAC8
SCHEMBL823701 0.83 HDAC1 (0.60) HDAC4HDAC1HDAC7HDAC11HDAC8
SCHEMBL823559 0.83 HDAC1 (0.54) HDAC4HDAC1HDAC7HDAC11HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250043174-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE COMPRISING SAME BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2025-02-06 US claimed
US-12139501-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-11-12 US claimed
US-20240368465-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE COMPRISING SAME Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-11-07 US claimed
US-20240058288-A1 DRUG COCKTAIL FOR TREATMENT OF PARKINSON'S DISEASE, LEWY BODY DISEASE AND MULTIPLE SYSTEM ATROPHY ALETA NEUROSCIENCE LLC (US) 2024-02-22 US claimed
US-11716900-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US claimed
US-11711969-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US claimed
US-20230006153-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-05 US claimed
WO-2022224118-A1 DRUG COCKTAIL FOR TREATMENT OF PARKINSON'S DISEASE, LEWY BODY DISEASE AND MULTIPLE SYSTEM ATROPHY ALETA NEUROSCIENCE, LLC (US) 2022-10-27 WO claimed
EP-4029501-A1 COMBINATION OF POLYAROMATIC UREA DERIVATIVES AND GLUCOCORTICOID OR HDAC INHIBITOR FOR THE TREATMENT OF DISEASES OR CONDITIONS ASSOCIATED WITH MUSCLE CELLS AND/OR SATELLITE CELLS Anagenesis Biotechnologies (FR) 2022-07-20 EP claimed
US-11374181-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-06-28 US claimed
US-20250313585-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-10-09 US disclosed
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof FLAGSHIP PIONEERING, INC. (US) 2025-04-17 US disclosed
US-20250109206-A1 ACTIVATABLE BISPECIFIC ANTI-CD3 AND ANTI-PD-L1 PROTEINS AND USES THEREOF CENTESSA PHARMACEUTICALS (UK) LIMITED (GB) 2025-04-03 US disclosed
CN-119677780-A Activatable bispecific anti-CD 3 and anti-PD-L1 proteins and uses thereof 森特萨制药(英国)有限公司 2025-03-21 CN disclosed
EP-4499232-A1 ACTIVATABLE BISPECIFIC ANTI-CD3 AND ANTI-PD-L1 PROTEINS AND USES THEREOF Centessa Pharmaceuticals (UK) Limited (GB) 2025-02-05 EP disclosed
WO-2010014220-A1 NEUROPROTECTIVE AGENTS FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES LIXTE BIOTECHNOLOGY, INC. (US) 2010-02-04 WO disclosed
US-20090143445-A1 HDAC Inhibitors JOHN P. WHITE, ESQ 2009-06-04 US disclosed
US-20090143445-A1 HDAC Inhibitors JOHN P. WHITE, ESQ 2009-06-04 US disclosed
WO-2009045440-A1 HDAC INHIBITORS LIXTE BIOTECHNOLOGY HOLDINGS, INC. (US) 2009-04-09 WO disclosed
WO-2009045440-A1 HDAC INHIBITORS LIXTE BIOTECHNOLOGY HOLDINGS, INC. (US) 2009-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11711969-B2 Organic electroluminescent materials and devices RPS4X, NCOA4, KCNN4 HDAC4 200/4885HDAC1 781/4885HDAC7 2107/4885
US-20250313585-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, AP2M1, LAGE3 HDAC4 2864/4885HDAC1 1312/4885HDAC7 3924/4885
US-12139501-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM HDAC4 4440/4885HDAC1 2450/4885HDAC7 4472/4885
US-20240058288-A1 DRUG COCKTAIL FOR TREATMENT OF PARKINSON'S DISEASE, LEWY BODY DISEASE AND MULTIPLE SYSTEM ATROPHY BAG3, BAG2, PHB1 HDAC4 1671/4885HDAC1 2195/4885HDAC7 2334/4885
US-20230006153-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC HDAC4 3287/4885HDAC1 3518/4885HDAC7 3984/4885
US-20090143445-A1 HDAC Inhibitors HDAC3, HDAC7, HDAC4 HDAC4 3/4885HDAC1 6/4885HDAC7 2/4885
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof EFTUD2, DDX21, SNRPE HDAC4 4133/4885HDAC1 3361/4885HDAC7 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.