Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27992662 | 0.97 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| SCHEMBL11973762 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| Anthraquinone SCHEMBL1376042 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| SCHEMBL294408 | 0.76 | CYP1A2 (0.48) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| SCHEMBL7306166 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| SCHEMBL5609984 | 0.76 | HPRT1 (0.41) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| SCHEMBL7305590 | 0.76 | TRPM4 (0.56) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| SCHEMBL149754 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| Triphenylene SCHEMBL28075721 | 0.74 | HPRT1 (0.59) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| SCHEMBL28383579 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339973-A1 | RING-FUSED 2-PYRIDONE COMPOUNDS, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | QURETECH BIO AB (SE) | 2023-10-26 | — | — | US | claimed |
| US-20230233536-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | QURETECH BIO AB (SE) | 2023-07-27 | — | — | US | claimed |
| EP-4146659-A1 | RING-FUSED 2-PYRIDONE COMPOUNDS, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | Quretech Bio AB (SE) | 2023-03-15 | — | — | EP | claimed |
| CN-115551869-A | Fused ring 2-pyridone compounds, process for their preparation and their use for the treatment and/or prevention of diseases involving gram-positive bacteria | 快尔生物技术公司 | 2022-12-30 | — | — | CN | claimed |
| US-20210401815-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | WASHINGTON UNIVERSITY | 2021-12-30 | — | — | US | claimed |
| WO-2021224501-A1 | RING-FUSED 2-PYRIDONE COMPOUNDS, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | QURETECH BIO AB (SE) | 2021-11-11 | — | — | WO | claimed |
| CN-113024587-A | Condensed aromatic derivative containing boron and nitrogen, method for preparing same, and organic electroluminescent device | 吉林奥来德光电材料股份有限公司 | 2021-06-25 | — | — | CN | claimed |
| EP-3638681-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | Quretech Bio AB (SE) | 2020-04-22 | — | — | EP | claimed |
| CN-110799513-A | Ring-fused thiazolo-2-pyridones, method for the production thereof and use thereof for treating and/or preventing diseases which involve gram-positive bacteria | 快尔生物技术公司 | 2020-02-14 | — | — | CN | claimed |
| WO-2018229141-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | QURETECH BIO AB (SE) | 2018-12-20 | — | — | WO | claimed |
| US-20020034657-A1 | Organic electroluminescence device | NEC CORPORATION. | 2002-03-21 | — | — | US | claimed |
| EP-0231497-A1 | Silicone resist materials containing polysiloxanes | KABUSHIKI KAISHA TOSHIBA (JP) | 1987-08-12 | — | — | EP | claimed |
| US-12043749-B2 | Method for producing ink composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-07-23 | — | — | US | disclosed |
| US-12043627-B2 | Compound and color conversion film comprising same | LG CHEM, LTD. (KR) | 2024-07-23 | — | — | US | disclosed |
| EP-4400526-A1 | POLYMER AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | LG Chem, Ltd. (KR) | 2024-07-17 | — | — | EP | disclosed |
| WO-2024147631-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | 에스에프씨 주식회사 | 2024-07-11 | — | — | WO | disclosed |
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0231497-A1 | Silicone resist materials containing polysiloxanes | KABUSHIKI KAISHA TOSHIBA (JP) | 1987-08-12 | — | — | EP | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |
| EP-0045431-A1 | Process for the side-chain bromination of toluenes and mixtures of toluenes diversly highly brominated in the side chain | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210401815-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | TLR4, NOD2, TLR5 | ALDH1A1 2426/4885HSD17B10 676/4885CYP1A2 2058/4885 |
| US-20230339973-A1 | RING-FUSED 2-PYRIDONE COMPOUNDS, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | PGLS, BLVRB, SDHB | ALDH1A1 2766/4885HSD17B10 575/4885CYP1A2 1097/4885 |
| US-20230233536-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | NOD2, TLR4, TLR5 | ALDH1A1 2321/4885HSD17B10 481/4885CYP1A2 2164/4885 |
| US-12043627-B2 | Compound and color conversion film comprising same | CRY1, FLI1, FDFT1 | ALDH1A1 47/4885HSD17B10 693/4885CYP1A2 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.