SCHEMBL824128

SCHEMBL824128

Cc1ccc(C(C)C)cc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.58
PTGS1 P23219 2/20 0.56
TRPA1 O75762 1/20 0.56
CACNA1C Q13936 1/20 0.56
CYP3A4 P08684 1/20 0.48
PTGS2 P35354 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 2/20 0.40
S1PR1 P21453 1/20 0.40
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
ALOX12 P18054 1/20 0.39
HIF1A Q16665 1/20 0.39
CHRNA1 P02708 1/20 0.39
CHRNG P07510 1/20 0.39
CHRNB1 P11230 1/20 0.39
CHRNB2 P17787 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19441008 0.86 LMNA (0.48) LMNAPTGS1TRPA1CACNA1CCYP3A4
SCHEMBL11631911 0.84 CYP3A4 (0.46) LMNAPTGS1TRPA1CACNA1CCYP3A4
SCHEMBL12879049 0.84 TRPV4 (0.50) LMNAPTGS1TRPA1CACNA1CCYP3A4
SCHEMBL25906691 0.82 RXRA (0.50) LMNAPTGS1TRPA1CACNA1CCYP3A4
SCHEMBL16955601 0.82 CYP3A4 (0.45) LMNAPTGS1TRPA1CACNA1CCYP3A4
SCHEMBL8286723 0.82 ADRB2 (0.52) LMNAPTGS1TRPA1CACNA1CCYP3A4
SCHEMBL19368278 0.82 CYP3A4 (0.45) LMNAPTGS1TRPA1CACNA1CCYP3A4
SCHEMBL11635848 0.82 CYP3A4 (0.45) LMNAPTGS1TRPA1CACNA1CCYP3A4
SCHEMBL19414246 0.82 UGT2B7 (0.45) LMNAPTGS1TRPA1CACNA1CCYP3A4
SCHEMBL31171868 0.81 CYP3A4 (0.48) LMNAPTGS1TRPA1CACNA1CCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4140695-A Process for producing copper phthalocyanines IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1979-02-20 US claimed
EP-4181943-B1 TREATMENT OF POST-OPERATIVE SURGICAL PAIN IPSEN BIOPHARM LTD (GB) 2025-12-17 EP disclosed
US-12403334-B2 Low intensity ultrasound therapy B G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) 2025-09-02 US disclosed
US-20240239772-A1 PROTEASE INHIBITORS AND METHODS OF USE THE CLEVELAND CLINIC FOUNDATION 2024-07-18 US disclosed
US-20240239772-A1 PROTEASE INHIBITORS AND METHODS OF USE THE CLEVELAND CLINIC FOUNDATION 2024-07-18 US disclosed
US-20240228495-A1 Tricyclic Inhibitors of Influenza Virus Endonuclease STANFORD RES INST INT (US) 2024-07-11 US disclosed
US-12030869-B2 5-membered heteroaryl carboxamide compounds for treatment of HBV ASSEMBLY BIOSCIENCES, INC. (US) 2024-07-09 US disclosed
US-12030869-B2 5-membered heteroaryl carboxamide compounds for treatment of HBV ASSEMBLY BIOSCIENCES, INC. (US) 2024-07-09 US disclosed
US-20240207267-A1 (R)-Glutarimide CRBN Ligands and Methods of Use BEIGENE SWITZERLAND GMBH (CH) 2024-06-27 US disclosed
EP-3863638-B1 PHOSPHODIESTERASE INHIBITORS UNIV NEBRASKA (US) 2024-06-26 EP disclosed
EP-0027952-B1 PROCESS FOR PREPARING N,O-DISUBSTITUTED URETHANES BAYER AG (DE) 1983-04-13 EP disclosed
EP-0027953-B1 PROCESS FOR PREPARING N,O-DISUBSTITUTED URETHANES BAYER AG (DE) 1983-02-16 EP disclosed
EP-0028331-B1 Process for preparing urethanes BAYER AG (DE) 1982-12-15 EP disclosed
EP-0063299-A1 Process for the preparation of N-aryl-2,4-oxazolidine diones BAYER AG (DE) 1982-10-27 EP disclosed
EP-0059400-A2 Process for the preparation of urethanes BAYER AG (DE) 1982-09-08 EP disclosed
EP-0027952-A1 Process for preparing N,O-disubstituted urethanes BAYER AG (DE) 1981-05-06 EP disclosed
EP-0027940-A1 Process for preparing urethanes BAYER AG (DE) 1981-05-06 EP disclosed
EP-0027953-A1 Process for preparing N,O-disubstituted urethanes BAYER AG (DE) 1981-05-06 EP disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 US disclosed
US-4140695-A Process for producing copper phthalocyanines IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1979-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207267-A1 (R)-Glutarimide CRBN Ligands and Methods of Use CRBN, CDR2, CRKL LMNA 2226/4885PTGS1 3690/4885TRPA1 4876/4885
US-20240228495-A1 Tricyclic Inhibitors of Influenza Virus Endonuclease RNASEH1, RNASEL, DNASE1 LMNA 1328/4885PTGS1 2297/4885TRPA1 4601/4885
US-20240239772-A1 PROTEASE INHIBITORS AND METHODS OF USE ACE2, ACE, TMPRSS2 LMNA 1927/4885PTGS1 1233/4885TRPA1 4031/4885
US-12030869-B2 5-membered heteroaryl carboxamide compounds for treatment of HBV HCCS, HAVCR2, MAVS LMNA 1876/4885PTGS1 3753/4885TRPA1 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.