Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240645 | 0.91 | TSHR (0.55) | KMT2AMEN1MAPK1TSHRLMNA | |
| SCHEMBL8247078 | 0.91 | TSHR (0.62) | KMT2AMEN1MAPK1TSHRLMNA | |
| SCHEMBL4761009 | 0.88 | MEN1 (0.56) | KMT2AMEN1MAPK1TSHRLMNA | |
| SCHEMBL4762716 | 0.81 | SMN1; SMN2 (0.51) | KMT2AMEN1MAPK1TSHRLMNA | |
| SCHEMBL4722342 | 0.79 | MEN1 (0.71) | KMT2AMEN1MAPK1TSHRLMNA | |
| SCHEMBL8250759 | 0.76 | ALDH1A1 (0.57) | KMT2AMEN1TSHRLMNAALDH1A1 | |
| SCHEMBL8239706 | 0.73 | POLB (0.43) | KMT2AMEN1ALDH1A1ENPP2SMN1; SMN2 | |
| SCHEMBL8250463 | 0.73 | HTT (0.60) | KMT2AMEN1MAPK1TSHRLMNA | |
| SCHEMBL4763187 | 0.72 | SMN1; SMN2 (0.55) | KMT2AMEN1MAPK1TSHRLMNA | |
| SCHEMBL4763376 | 0.72 | SLC6A7 (0.48) | KMT2AMEN1TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009635-A1 | PHENYL SUBSTITUTED PIPERAZINE-DERIVATIVES AS INHIBITORS OF PLAMINOGENIC ACTIVATOR INHIBITORS-I (PAI-I) | BAYER HEALTHCARE AG (DE) | 2007-01-25 | — | — | WO | disclosed |