Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429703 | 0.90 | MMP13 (0.43) | REV1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8207368 | 0.90 | REV1 (0.47) | REV1LMNAALDH1A1MAPTPOLB | |
| SCHEMBL8212994 | 0.89 | POLB (0.54) | REV1LMNAALDH1A1MAPTPOLB | |
| SCHEMBL8207562 | 0.89 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTPOLBGAA | |
| Bicarbonate SCHEMBL7429705 | 0.87 | SMN1; SMN2 (0.45) | REV1LMNAALDH1A1MAPTPOLB | |
| SCHEMBL8206305 | 0.87 | NPC1 (0.48) | REV1LMNAALDH1A1MAPTPOLB | |
| SCHEMBL8200143 | 0.84 | PKM (0.52) | LMNAMAPTPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL8207597 | 0.84 | LMNA (0.45) | REV1LMNAMAPTPOLBGAA | |
| SCHEMBL8206201 | 0.82 | MAPT (0.46) | REV1LMNAALDH1A1MAPTPOLB | |
| SCHEMBL7890839 | 0.81 | ALDH1A1 (0.45) | REV1LMNAALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |