Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27998786 | 0.78 | MAPT (0.40) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4043808 | 0.69 | LMNA (0.36) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12987195 | 0.69 | FAAH (0.51) | FAAHALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL29120775 | 0.66 | LMNA (0.53) | FAAHALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL28844089 | 0.66 | HSD11B1 (0.39) | — | |
| SCHEMBL10604536 | 0.66 | CTSL (0.49) | FAAHALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL17031709 | 0.65 | FAAH (0.47) | FAAHALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL10590807 | 0.65 | CTSK (0.54) | FAAHALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL30984052 | 0.65 | FAAH (0.47) | FAAHALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL867351 | 0.65 | FAAH (0.47) | FAAHALDH1A1GAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117567-A2 | ALPHA AMINOACID ESTER-DRUG CONJUGATES HYDROLYSABLE BY CARBOXYLESTERASE | CHROMA THERAPEUTICS LTD (GB) | 2006-11-09 | — | — | WO | disclosed |