Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 6/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CDC25A | P30304 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17430583 | 0.88 | ALDH1A1 (0.45) | AURKAAURKBAPEX1IDO1ALDH1A1 | |
| Aurantiogliocladin SCHEMBL487583 | 0.81 | MAPT (0.50) | APEX1IDO1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL9863966 | 0.78 | HKDC1 (0.48) | AURKAAURKBAPEX1IDO1ALDH1A1 | |
| SCHEMBL9655485 | 0.75 | CDC25A (0.64) | APEX1IDO1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1393351 | 0.74 | ALDH1A1 (0.62) | AURKAAURKBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL31415086 | 0.72 | ALDH1A1 (0.52) | AURKAAURKBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL3420496 | 0.71 | MAPT (0.58) | APEX1IDO1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL12592463 | 0.70 | CDC25A (0.58) | APEX1IDO1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL9180312 | 0.70 | DUSP3 (0.48) | APEX1IDO1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL4725792 | 0.70 | APEX1 (0.44) | APEX1IDO1ALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108037082-B | Novel method for measuring hydrogen pumping capacity of mitochondria | 临沂大学 | 2020-01-14 | — | — | CN | claimed |
| CN-110950749-B | IDO inhibitor and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-07-25 | — | — | CN | disclosed |
| CN-110950749-A | IDO inhibitor and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2020-04-03 | — | — | CN | disclosed |
| CN-108037082-B | Novel method for measuring hydrogen pumping capacity of mitochondria | 临沂大学 | 2020-01-14 | — | — | CN | disclosed |
| CN-108037082-B | Novel method for measuring hydrogen pumping capacity of mitochondria | 临沂大学 | 2020-01-14 | — | — | CN | disclosed |
| CN-108037082-A | A kind of new method for measuring mitochondria pump Hydrogen Energy power | 临沂大学 | 2018-05-15 | — | — | CN | disclosed |
| US-20080200732-A1 | Novel Intermediates Useful for the Preparation of Coenzymes, Process for the Preparation of Novel Intermediates and an Improved Process for the Preparation of Coenzymes | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2008-08-21 | — | — | US | disclosed |
| US-20080200732-A1 | Novel Intermediates Useful for the Preparation of Coenzymes, Process for the Preparation of Novel Intermediates and an Improved Process for the Preparation of Coenzymes | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2008-08-21 | — | — | US | disclosed |
| WO-2007004091-A2 | NOVEL INTERMEDIATES USEFUL FOR THE PREPARATION OF COENZYMES, PROCESS FOR THE PREPARATION OF NOVEL INTERMEDIATES AND AN IMPROVED PROCESS FOR THE PREPARATION OF COENZYMES | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200732-A1 | Novel Intermediates Useful for the Preparation of Coenzymes, Process for the Preparation of Novel Intermediates and an Improved Process for the Preparation of Coenzymes | NDUFA10, NDUFA9, NDUFB10 | AURKA 4489/4885AURKB 4325/4885APEX1 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.