SCHEMBL825285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20821022	0.84	PDK1 (0.49)	KDM4EPDK1PDK2PDK3PDK4
	SCHEMBL24506561	0.84	KDM4E (0.65)	KDM4EALDH1A1HSD17B10KMT2ACETP
	SCHEMBL9987490	0.82	PDK1 (0.73)	KDM4EPDK1PDK2PDK3PDK4
	SCHEMBL20692016	0.79	HSD17B10 (0.55)	KDM4EALDH1A1HSD17B10CFTRKMT2A
	SCHEMBL940016	0.79	KDM4E (0.68)	KDM4EALDH1A1HSD17B10CFTRKMT2A
	SCHEMBL18950889	0.79	HSD17B10 (0.55)	KDM4EALDH1A1HSD17B10CFTRKMT2A
	SCHEMBL2895994	0.78	ALDH1A1 (0.67)	KDM4EALDH1A1HSD17B10CFTRKMT2A
	SCHEMBL7311425	0.78	TSHR (0.59)	KDM4EALDH1A1HSD17B10KMT2APOLB
	SCHEMBL15808796	0.78	KDM4E (0.58)	KDM4EALDH1A1HSD17B10CFTRKMT2A
	SCHEMBL7318242	0.77	TSHR (0.58)	KDM4EALDH1A1HSD17B10KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.