Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31094962 | 0.81 | RAB9A (0.71) | RAB9AHPGDCYP1A2POLBCYP3A4 | |
| SCHEMBL7400924 | 0.79 | HPGD (0.54) | RAB9AHPGDCYP1A2POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL7397125 | 0.78 | HPGD (0.53) | RAB9AHPGDCYP1A2POLBALDH1A1 | |
| SCHEMBL21959263 | 0.77 | RAB9A (0.44) | RAB9AHPGDCYP1A2POLBCYP3A4 | |
| SCHEMBL641112 | 0.73 | PARP1 (0.48) | RAB9AALDH1A1ERCC5FEN1PARP1 | |
| SCHEMBL2952721 | 0.72 | PARP1 (0.52) | RAB9AALDH1A1ERCC5FEN1PARP1 | |
| Hydrochloric Acid SCHEMBL10921538 | 0.70 | ALDH1A1 (0.46) | RAB9AHPGDPOLBCYP2C19ALDH1A1 | |
| SCHEMBL11558102 | 0.69 | PARP1 (0.44) | RAB9APOLBCYP2C19ALDH1A1ERCC5 | |
| SCHEMBL9874864 | 0.69 | NPC1 (0.57) | RAB9AALDH1A1LMNA | |
| SCHEMBL4645984 | 0.69 | NPSR1 (0.46) | RAB9AHPGDALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890697-B1 | AZINONE AND DIAZINONE V3 INHIBITORS FOR DEPRESSION AND STRESS DISORDERS | PHARMACOPEIA LLC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8350043-B2 | Azinone and diazinone V3 inhibitors for depression and stress disorders | PHARMACOPEIA, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350043-B2 | Azinone and diazinone V3 inhibitors for depression and stress disorders | PHARMACOPEIA, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20070037822-A1 | Azinone and diazinone V3 inhibitors for depression and stress disorders | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2007-02-15 | — | — | US | disclosed |
| US-20070037822-A1 | Azinone and diazinone V3 inhibitors for depression and stress disorders | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2007-02-15 | — | — | US | disclosed |
| WO-2006133242-A2 | AZINONE AND DIAZINONE V3 INHIBITORS FOR DEPRESSION AND STRESS DISORDERS | PHARMACOPEIA, INC. (US) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037822-A1 | Azinone and diazinone V3 inhibitors for depression and stress disorders | HTR3C, HTR3A, AZI2 | RAB9A 2071/4885HPGD 445/4885CYP1A2 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.