Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400924 | 0.81 | HPGD (0.54) | HPGDHTTALDH1A1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL7397125 | 0.79 | HPGD (0.53) | HPGDHTTALDH1A1LMNARAB9A | |
| SCHEMBL21959263 | 0.78 | RAB9A (0.44) | HPGDPKMALDH1A1LMNARAB9A | |
| SCHEMBL9068167 | 0.78 | PKM (0.68) | NPSR1HPGDHTTPKMALDH1A1 | |
| SCHEMBL17459822 | 0.75 | MAPT (0.59) | HTTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL15149819 | 0.73 | MMP13 (0.51) | HPGDHTTALDH1A1LMNARAB9A | |
| SCHEMBL16249979 | 0.72 | CYP1A2 (0.41) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15149671 | 0.72 | LMNA (0.44) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| P-Xylene SCHEMBL11137342 | 0.71 | NPSR1 (0.44) | NPSR1HPGDHTTPKMALDH1A1 | |
| SCHEMBL17826852 | 0.70 | LMNA (0.43) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285909-B1 | PROCESS FOR THE PRODUCTION OF NITROGEN COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-08-20 | — | — | EP | disclosed |
| US-7087783-B2 | Method for preparing nitrogen-containing compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-08-08 | — | — | US | disclosed |
| US-6960689-B2 | Method for preparing nitrogen-containing compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-11-01 | — | — | US | disclosed |
| US-6946576-B2 | Method for preparing nitrogen-containing compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-09-20 | — | — | US | disclosed |
| US-20050075513-A1 | Method for preparing nitrogen-containing compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-04-07 | — | — | US | disclosed |
| US-20050049421-A1 | Method for preparing nitrogen-containing compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-03-03 | — | — | US | disclosed |
| US-20050043569-A1 | Method for preparing nitrogen-containing compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-02-24 | — | — | US | disclosed |
| US-6803472-B2 | REACTING NH GROUP-CONTAINING COMPOUNDS WITH THIOCYANATES, CYANAMIDES, NITRITES OR ESTERS IN PRESENCE OF SILYLATING AGENT TO SYNTHESIZE CORRESPONDING NITROGEN-CONTAINING ADDITION OR SUBSTITUTION PRODUCTS; DIRECT, EFFICIENCY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-10-12 | — | — | US | disclosed |
| US-20030158442-A1 | Process for the production of nitrogen compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1285909-A1 | PROCESS FOR THE PRODUCTION OF NITROGEN COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075513-A1 | Method for preparing nitrogen-containing compounds | NOS2, NOS1, NNMT | NPSR1 1731/4885HPGD 338/4885HTT 1949/4885 |
| US-20050049421-A1 | Method for preparing nitrogen-containing compounds | NOS2, NOS1, NNMT | NPSR1 1731/4885HPGD 338/4885HTT 1949/4885 |
| US-20050043569-A1 | Method for preparing nitrogen-containing compounds | NOS2, NOS1, NNMT | NPSR1 1731/4885HPGD 338/4885HTT 1949/4885 |
| US-20030158442-A1 | Process for the production of nitrogen compounds | NOS2, NOS1, NNMT | NPSR1 1879/4885HPGD 429/4885HTT 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.