Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of D-Glutamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL82753 | 1.00 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL7611844 | 1.00 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL23611029 | 1.00 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL7068284 | 1.00 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL1301472 | 0.98 | CA1 (0.46) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL2853218 | 0.98 | CA1 (0.50) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL2853212 | 0.98 | CA1 (0.50) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL1899057 | 0.98 | CA1 (0.46) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL11742432 | 0.98 | CA1 (0.46) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL1394400 | 0.98 | CA1 (0.46) | CA1BBOX1GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7260 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124148-A1 | POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY | BHAMIS RES LABORATORY PVT LTD (IN) | 2026-05-07 | — | — | US | claimed |
| EP-3892114-B1 | EFFERVESCENT BEVERAGE HAVING IMPROVED TASTE QUALITIES OF SUGAR AND SWEETENER | SUNTORY HOLDINGS LTD (JP) | 2026-04-22 | — | — | EP | claimed |
| EP-4721752-A2 | HERSTELLUNG UND VERWENDUNG VON IN VITRO-SYNTHETISIERTER SSRNA ZUR EINFÜHRUNG IN SÄUGETIERZELLEN ZUR INDUKTION EINER BIOLOGISCHEN ODER BIOCHEMISCHEN WIRKUNG | CELLSCRIPT, LLC (US) | 2026-04-08 | — | — | EP | claimed |
| US-12582134-B2 | Non-dairy creamer and method of making the same | CARGILL, INCORPORATED (US) | 2026-03-24 | — | — | US | claimed |
| EP-4710916-A1 | COMPOSITION COMPRISING GLUTAMATE FOR CARIES PREVENTION | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) (ES) | 2026-03-18 | — | — | EP | claimed |
| EP-4259092-B1 | PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR TOPICAL USE COMPRISING A POLYMER IN THE FORM OF A PULVERULENT SOLID AS THICKENING AGENT | SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2026-02-18 | — | — | EP | claimed |
| EP-4696146-A2 | EFFERVESCENT BEVERAGE HAVING IMPROVED QUALITY OF TASTE EXHIBITED BY SUGAR AND SWEETNER | Suntory Holdings Limited (JP) | 2026-02-18 | — | — | EP | claimed |
| US-20260014404-A1 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | PERIMETER SOLUTIONS, LP (US) | 2026-01-15 | — | — | US | claimed |
| US-20260007739-A1 | HERPESVIRUS COMPOSITIONS AND RELATED METHODS | SANOFI PASTEUR LTD (CA) | 2026-01-08 | — | — | US | claimed |
| WO-2025264733-A1 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | PERIMETER SOLUTIONS, LP (US) | 2025-12-26 | — | — | WO | claimed |
| EP-0081236-A1 | A compound seasoning composition, a process for its production and its use as a food component | AJINOMOTO CO., INC. (JP) | 1983-06-15 | — | — | EP | claimed |
| US-4340614-A | POTASSIUM SALTS | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-20 | — | — | US | claimed |
| US-4297100-A | Aqueous dye preparations | CIBA-GEIGY CORPORATION (US) | 1981-10-27 | — | — | US | claimed |
| US-4216244-A | Low sodium salt seasoning | ALLEN ALFRED E JR | 1980-08-05 | — | — | US | claimed |
| US-4099454-A | Electrical resistance cooking appliance for use with an electrode type cooking package | LECTROFOOD, CORP. (US) | 1978-07-11 | — | — | US | claimed |
| US-4100302-A | FOODS, GELS, IONIZING | LECTROFOOD CORP. (US) | 1978-07-11 | — | — | US | claimed |
| US-4066793-A | Seasoning composition and preparation thereof | AJINOMOTO CO., INC. (JA) | 1978-01-03 | — | — | US | claimed |
| US-4016297-A | Electrically conducting foodstuff coated with composition of matter consisting essentially of gel and ionized species | LECTROFOOD, INC. (US) | 1977-04-05 | — | — | US | claimed |
| US-4016301-A | Electrically conductible gellable composition with ionized salt | LECTROFOOD, INC. (US) | 1977-04-05 | — | — | US | claimed |
| US-3966972-A | Packaged coated food product capable of being cooked using electrodes | LECTROFOOD, INC. (US) | 1976-06-29 | — | — | US | claimed |