Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29012860 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10ENPP2 | |
| SCHEMBL31094660 | 0.88 | MAOA (0.67) | ALDH1A1KDM4EHPGDHSD17B10MAOA | |
| SCHEMBL1222893 | 0.88 | MAOA (0.67) | ALDH1A1KDM4EHPGDHSD17B10MAOA | |
| SCHEMBL28756834 | 0.87 | ESR1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10ENPP2 | |
| Hydrochloric Acid SCHEMBL28263903 | 0.86 | MAOA (0.65) | ALDH1A1KDM4EHPGDHSD17B10MAOA | |
| SCHEMBL1513359 | 0.86 | JAK2 (0.53) | HPGDJAK2JAK3POLBTP53 | |
| SCHEMBL3578515 | 0.86 | MAOA (0.65) | ALDH1A1KDM4EHSD17B10MAOATAS1R3 | |
| SCHEMBL27683925 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10ENPP2 | |
| SCHEMBL4921487 | 0.83 | MAOA (0.68) | ALDH1A1MAOACA12CA1CA2 | |
| SCHEMBL13516358 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470926-A | Substituted pyrrolopyrimidines | Bayer Pharma AG | 2015-03-25 | — | — | CN | claimed |
| CN-116253673-B | Indole sulfonated monomer, indole sulfonated polymer, proton exchange membrane and preparation method thereof | 南阳师范学院 | 2024-10-18 | — | — | CN | disclosed |
| CN-116283722-B | Preparation method of 2- (2' -aminophenyl) carbazole compound under acidic condition | 重庆医科大学 | 2024-06-11 | — | — | CN | disclosed |
| US-20230257355-A1 | HYDROXAMIC ACID-CONTAINING COMPOUND, AND PREPARATION METHOD AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-08-17 | — | — | US | disclosed |
| US-20230257355-A1 | HYDROXAMIC ACID-CONTAINING COMPOUND, AND PREPARATION METHOD AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-08-17 | — | — | US | disclosed |
| CN-116283722-A | Preparation method of 2- (2' -aminophenyl) carbazole compound under acidic condition | 重庆医科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116253673-A | Indole sulfonated monomer, indole sulfonated polymer, proton exchange membrane and preparation method thereof | 南阳师范学院 | 2023-06-13 | — | — | CN | disclosed |
| CN-116134016-A | Tricyclic heterocycles | 默克专利股份公司 | 2023-05-16 | — | — | CN | disclosed |
| EP-2669270-B1 | INDOLE-RELATED COMPOUNDS AS URAT1 INHIBITORS | SATO PHARMA (JP) | 2018-01-03 | — | — | EP | disclosed |
| US-9359350-B2 | Ring-fused compound | SATO PHARMACEUTICAL CO., LTD. (JP) | 2016-06-07 | — | — | US | disclosed |
| EP-1379239-B1 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | LILLY CO ELI (US) | 2007-09-12 | — | — | EP | disclosed |
| US-20070099909-A1 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | CHEN ZHAOGEN | 2007-05-03 | — | — | US | disclosed |
| US-7157488-B2 | N-(2-Arylethyl) benzylamines as antagonists of the 5-HT6 receptor | ELI LILLY AND COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-20060009511-A9 | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor | CHEN ZHAOGEN | 2006-01-12 | — | — | US | disclosed |
| US-20050178659-A1 | Copolymer compound and electrochemical cell therewith | NEC TOKIN CORPORATION (JP) | 2005-08-18 | — | — | US | disclosed |
| US-20050148775-A1 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| CN-1610547-A | N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor | LILLY CO ELI (US) | 2005-04-27 | — | — | CN | disclosed |
| EP-1481978-A1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | Mitsubishi Rayon Co., Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-5538973-A | ANTIHISTAMINE, THROMBOXANE A2 ANTAGONIST | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0597112-A1 | NOVEL IMIDAZOLE DERIVATIVE, PHARMACEUTICAL USE THEREOF, AND INTERMEDIATE THEREFOR | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1994-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148775-A1 | Process for production of heteroaryl-type boron compounds with iridium catalyst | PIN4, IPO5, HLCS | ALDH1A1 3867/4885KDM4E 2745/4885HPGD 3680/4885 |
| US-20060009511-A9 | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor | HTR6, HTR2C, HTR1B | ALDH1A1 1218/4885KDM4E 1970/4885HPGD 1442/4885 |
| US-20230257355-A1 | HYDROXAMIC ACID-CONTAINING COMPOUND, AND PREPARATION METHOD AND USE THEREOF | SI, SCD, SMPD1 | ALDH1A1 1686/4885KDM4E 792/4885HPGD 704/4885 |
| US-20070099909-A1 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | HTR6, HTR2C, HTR1B | ALDH1A1 1218/4885KDM4E 1970/4885HPGD 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.