Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCND2 | P30279 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286211 | 0.92 | MAP3K8 (0.34) | GAAMAT2AHPGDMAPK1GFER | |
| SCHEMBL8286173 | 0.90 | GAA (0.36) | GAAMAT2AHPGDMAPK1GFER | |
| SCHEMBL8286182 | 0.89 | MAT2A (0.46) | GAAMAT2AHPGDMAPK1GFER | |
| SCHEMBL8287246 | 0.87 | GAA (0.39) | GAAHPGDMAPK1GFERPDE11A | |
| SCHEMBL8287276 | 0.87 | MAT2A (0.40) | GAAMAT2AHPGDMAPK1MAPT | |
| SCHEMBL8286184 | 0.86 | ALDH1A1 (0.39) | GAAMAPTALDH1A1RAB9A | |
| SCHEMBL8286174 | 0.86 | BRAF (0.39) | GAAMAT2AHPGDMAPK1GFER | |
| SCHEMBL8287280 | 0.85 | RAB9A (0.43) | GAAHPGDMAPK1PDE11AMAPT | |
| SCHEMBL8285367 | 0.84 | KCNJ6 (0.37) | GAAHPGDMAPK1GFERMAPT | |
| SCHEMBL8287991 | 0.82 | GAA (0.39) | GAAHPGDMAPK1GFERPDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005091857-A2 | 1,6-NAPHTHYRIDINE AND 1,8-NAPHTHYRIDINE DERIVATIVES AND THEIR USE TO TREAT DIABETES AND RELATED DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |
| WO-2003027112-A1 | 1, 8-NAPHTHYRIDINE DERIVATIVES AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |