Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESPL1 | Q14674 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 11/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL831029 | 0.84 | MAPT (0.36) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL829442 | 0.83 | EPAS1 (0.39) | ESPL1EPAS1ALDH1A1LMNAPOLB | |
| SCHEMBL830424 | 0.79 | CYP3A4 (0.33) | — | |
| SCHEMBL830877 | 0.79 | NR3C1 (0.31) | — | |
| SCHEMBL830833 | 0.79 | HTT (0.34) | ALDH1A1POLBHTT | |
| SCHEMBL831060 | 0.77 | CXCR2 (0.34) | KMT2A | |
| SCHEMBL829803 | 0.76 | MEN1 (0.30) | LMNAMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL580069 | 0.73 | LIPG (0.33) | — | |
| SCHEMBL3829832 | 0.72 | HSD11B1 (0.31) | — | |
| SCHEMBL829759 | 0.72 | PDE2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099807-B1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSEONICS INC (US) | 2014-01-01 | — | — | EP | disclosed |
| US-8143068-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-7851225-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| EP-2099807-A2 | OXIDATION RESISTANT INDICATOR MOLECULES | Sensors For Medicine And Science, Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2008-06-19 | — | — | US | disclosed |
| WO-2008066921-A2 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | AOX1, GPX4, SQOR | ESPL1 2916/4885EPAS1 2679/4885ALDH1A1 129/4885 |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | AOX1, GPX4, SQOR | ESPL1 2916/4885EPAS1 2679/4885ALDH1A1 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.