Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298648 | 0.87 | CDK9 (0.36) | LRRK2ITGB3ITGA2BFFAR4 | |
| SCHEMBL8302338 | 0.86 | ITGB3 (0.42) | DGAT1ITGB3ITGA2BFFAR4 | |
| SCHEMBL8300331 | 0.72 | KDM4E (0.43) | DGAT1ITGB3ITGA2BFFAR4 | |
| SCHEMBL8305658 | 0.72 | CCNT1 (0.38) | DGAT1LRRK2ITGB3ITGA2BFFAR4 | |
| SCHEMBL8305139 | 0.71 | CDK9 (0.36) | LRRK2FFAR4 | |
| SCHEMBL8304380 | 0.69 | DRD3 (0.36) | — | |
| SCHEMBL8302166 | 0.69 | ITGB3 (0.39) | DGAT1ITGB3ITGA2B | |
| SCHEMBL8300679 | 0.68 | CCR3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL7790830 | 0.68 | DRD2 (0.44) | ITGB3ITGA2BFFAR4 | |
| SCHEMBL7787452 | 0.68 | KDM4E (0.46) | ITGB3ITGA2BFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |