Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722367 | 0.66 | ALDH1A1 (0.60) | RAB9ANPC1ALDH1A1KMT2ATSHR | |
| SCHEMBL8305735 | 0.65 | CYP1A2 (0.34) | RAB9ANPC1ALDH1A1KMT2ATSHR | |
| SCHEMBL8438884 | 0.64 | SMN1; SMN2 (0.34) | RAB9ANPC1ALDH1A1KMT2ALMNA | |
| SCHEMBL14856081 | 0.61 | LMNA (0.44) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11390320 | 0.60 | L3MBTL1 (0.46) | RAB9ANPC1ALDH1A1TSHRLMNA | |
| SCHEMBL6417593 | 0.60 | TSHR (0.46) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL20553058 | 0.60 | KDM4E (0.43) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6412627 | 0.59 | NPC1 (0.49) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6418036 | 0.59 | NPC1 (0.49) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11232090 | 0.58 | TUBB4A (0.47) | RAB9AALDH1A1TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736022-A1 | 5-(2-IMIDAZOLINYLAMINO)BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995016685-A1 | 5-(2-IMIDAZOLINYLAMINO)BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1995-06-22 | — | — | WO | disclosed |